Evidence map›Paper›PMID 28345639›Full record

ArticleScientific reports2017

Genomic characterization of Nontuberculous Mycobacteria.

Tarcisio Fedrizzi, Conor J Meehan, Antonella Grottola, Elisabetta Giacobazzi, Giulia Fregni Serpini, Sara Tagliazucchi, Anna Fabio, Clotilde Bettua, Roberto Bertorelli, Veronica De Sanctis and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 1 pooled it
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 1 synthesis or guideline pooled it, 233 citations in OpenAlex.

  1. Pooled it
  2. Current Perspectives onInternational journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Tuberculosis: An Ongoing Global Threat.Advances in experimental medicine and biology · 2026
    Review
  8. Article
  9. Pathogens (Basel, Switzerland) · 2025
    Review
  10. Article
  11. An unusual genetic switch controlsbioRxiv : the preprint server for biology · 2025
    Article
  12. Genome sequence ofMicrobiology resource announcements · 2025
    Article
  13. Whole genome sequence data ofData in brief · 2025
    Article
  14. Article
  15. Article
  16. Four novel nontuberculous mycobacteria species:International journal of systematic and evolutionary microbiology · 2025
    Article
  17. NGS-based approach for diagnostically unidentifiedFrontiers in cellular and infection microbiology · 2025
    Article
  18. Frontiers in tuberculosis · 2025
    Review
  19. Frontiers in pharmacology · 2025
    Article
  20. Article

65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Tarcisio FedrizziCentre for Integrative Biology, University of Trento, Trento, Italy.
Conor J MeehanMycobacteriology unit, Department of Biomedical Science, Institute of Tropical Medicine, Antwerp, Belgium.
Antonella GrottolaMicrobiology and Virology Unit, University Hospital Polyclinic, Modena, Italy.
Elisabetta GiacobazziCentre for Integrative Biology, University of Trento, Trento, Italy.
Giulia Fregni SerpiniMicrobiology and Virology Unit, University Hospital Polyclinic, Modena, Italy.
Sara TagliazucchiMicrobiology and Virology Unit, University Hospital Polyclinic, Modena, Italy.
Anna FabioMicrobiology and Virology Unit, University Hospital Polyclinic, Modena, Italy.
Clotilde BettuaCentre for Integrative Biology, University of Trento, Trento, Italy.
Roberto BertorelliNGS Facility, Laboratory of Biomolecular Sequence and Structure Analysis for Health, Centre for Integrative Biology, University of Trento, Italy.
Veronica De SanctisNGS Facility, Laboratory of Biomolecular Sequence and Structure Analysis for Health, Centre for Integrative Biology, University of Trento, Italy.
Fabio RumpianesiMicrobiology and Virology Unit, University Hospital Polyclinic, Modena, Italy.
Monica PecorariMicrobiology and Virology Unit, University Hospital Polyclinic, Modena, Italy.
Olivier JoussonCentre for Integrative Biology, University of Trento, Trento, Italy.
Enrico TortoliEmerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.
Nicola SegataCentre for Integrative Biology, University of Trento, Trento, Italy.
University of Trento · ITPoliclinico di Modena · ITInstituut voor Tropische Geneeskunde · BEVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium tuberculosis and Mycobacterium leprae have remained, for many years, the primary species of the genus Mycobacterium of clinical and microbiological interest. The other members of the genus, referred to as nontuberculous mycobacteria (NTM), have long been underinvestigated. In the last decades, however, the number of reports linking various NTM species with human diseases has steadily increased and treatment difficulties have emerged. Despite the availability of whole genome sequencing technologies, limited effort has been devoted to the genetic characterization of NTM species. As a consequence, the taxonomic and phylogenetic structure of the genus remains unsettled and genomic information is lacking to support the identification of these organisms in a clinical setting. In this work, we widen the knowledge of NTMs by reconstructing and analyzing the genomes of 41 previously uncharacterized NTM species. We provide the first comprehensive characterization of the genomic diversity of NTMs and open new venues for the clinical identification of opportunistic pathogens from this genus.

Indexed as

Chromosome MappingGenetic VariationGene Transfer, HorizontalGenome, BacterialHumansMolecular Sequence AnnotationMycobacterium Infections, NontuberculousNontuberculous MycobacteriaOpen Reading FramesPhylogenySequence Analysis, DNA

Identifiers

PMID28345639
PMCPMC5366915
OpenAlexW2600736805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.