ArticleAddiction (Abingdon, England)2017
A National Swedish Longitudinal Twin-Sibling Study of alcohol use disorders among males.
Article in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Trajectories of genetic risk across dimensions of alcohol use behaviors.Addiction (Abingdon, England) · 2026Article
- Binge drinking trajectories across adolescence and early adulthood: Associations with genetic influences for dual-systems impulsive personality traits, alcohol consumption, and alcohol use disorder.Journal of psychopathology and clinical science · 2025Article
- Prevalence and heritability of alcohol use disorders in 18-year old Swedish twins.Nordisk alkohol- & narkotikatidskrift : NAT · 2023Article
- Birth order and health events attributable to alcohol and narcotics in midlife: A 25-year follow-up of a national Swedish birth cohort and their siblings.SSM - population health · 2022Article
- Psychometric Modelling of Longitudinal Genetically Informative Twin Data.Frontiers in genetics · 2019Article
- Alcohol Misuse Across the Lifespan: Insights from Developmental Studies in Behavior Genetics.Policy insights from the behavioral and brain sciences · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
aimsTo examine whether genetic influences on the development of alcohol use disorders (AUD) among men during emerging adulthood through mid-adulthood are stable or dynamic.
designA twin study modeling developmental changes in the genetic and environmental influences on AUD during three age periods (18-25, 26-33 and 33-41) as a Cholesky decomposition.
settingSweden.
participantsSwedish male twin pairs (1532 monozygotic and 1940 dizygotic) and 66 033 full male sibling pairs born less than 2 years apart. MEASUREMENTS: AUD was identified based on Swedish medical and legal registries.
findingsThe best-fitting model included additive genetic and unique environmental factors, with no evidence for shared environmental factors. Although the total heritability was stable over time, there were two major genetic factors contributing to AUD risk, one beginning at ages 18-25 with a modest decline in importance over time [0.84; confidence interval (CI) = 0.83-0.88], and another of less impact beginning at ages 26-33 with a modest increase in importance by ages 33-41 (0.31; CI = 0.05-0.47).
conclusionsThe heritability of alcohol use disorders among Swedish men appears to be stable among three age periods: 18-25 years, 26-33 years, and 33-41 years. Two sets of genetic risk factors contribute to alcohol use disorders risk, with one originating during the ages 18-25 years and another coming online at 26-33 years, providing support for the developmentally dynamic hypothesis.
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Registered trials
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