ArticleUnited European gastroenterology journal2017
Differential diagnosis of solid pancreatic masses: contrast-enhanced harmonic (CEH-EUS), quantitative-elastography (QE-EUS), or both?
Article in United European gastroenterology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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43 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- The efficiency of contrast-enhanced endoscopic ultrasound (EUS) combined with EUS elastography for pancreatic cancer diagnosis: a systematic review and meta-analysis.Ultrasonography (Seoul, Korea) · 2023Pooled it
- Endoscopic ultrasound in differentiation of solid pancreatic head lesions: A single centre experience.World journal of gastrointestinal endoscopy · 2026Article
- Endo-hepatology: Bridging the gap between lumen and liver.World journal of gastroenterology · 2025Review
- Endoscopic Ultrasound as a Diagnostic Tool for the Mediastinum and Thorax.Journal of clinical medicine · 2025Review
- Endoscopic Ultrasound-Guided Pancreatic Tissue Sampling: Lesion Assessment, Needles, and Techniques.Medicina (Kaunas, Lithuania) · 2024Review
- Diagnostics and Management of Pancreatic Cystic Lesions-New Techniques and Guidelines.Journal of clinical medicine · 2024Review
- Role of Endoscopic Ultrasound in Pancreatic Cancer Diagnosis and Management.Diagnostics (Basel, Switzerland) · 2024Review
- Contrast-enhanced guided endoscopic ultrasound procedures.World journal of gastroenterology · 2024Review
- Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma.Diagnostics (Basel, Switzerland) · 2023Review
- Artificial Intelligence in Endoscopic Ultrasonography-Guided Fine-Needle Aspiration/Biopsy (EUS-FNA/B) for Solid Pancreatic Lesions: Opportunities and Challenges.Diagnostics (Basel, Switzerland) · 2023Review
- Pancreatic cancer, autoimmune or chronic pancreatitis, beyond tissue diagnosis: Collateral imaging and clinical characteristics may differentiate them.World journal of gastrointestinal oncology · 2023Review
- Endoscopic Ultrasound (EUS) Guided Elastography.Diagnostics (Basel, Switzerland) · 2023Review
- Metastatic Renal Cell Carcinoma to Pancreas: Case Series and Review of the Literature.Diagnostics (Basel, Switzerland) · 2023Article
- Standardization of endoscopic ultrasound shear wave elastography.Clinical endoscopy · 2023Article
- Contrast Enhanced EUS for Predicting Solid Pancreatic Neuroendocrine Tumor Grade and Aggressiveness.Diagnostics (Basel, Switzerland) · 2023Review
- Challenges for clinicians treating autoimmune pancreatitis: Current perspectives.World journal of clinical cases · 2023Review
- Advanced EUS Imaging Techniques.Digestive diseases and sciences · 2022Review
- Malignant biliary obstruction due to metastatic non-hepato-pancreato-biliary cancer.World journal of gastroenterology · 2022Review
- Efficacy of Contrast-Enhanced Harmonic Endoscopic Ultrasound for Pancreatic Solid Tumors with a Combination of Qualitative and Quantitative Analyses: A Prospective Pilot Study.Digestive diseases and sciences · 2022Article
- Current role of endoscopic ultrasound in the diagnosis and management of pancreatic cancer.World journal of gastrointestinal endoscopy · 2022Review
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundContrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) and quantitative-elastography endoscopic ultrasound (QE-EUS) are considered useful tools for the evaluation of solid pancreatic tumors (SPT). The aim of our study was to evaluate the diagnostic accuracy of CEH-EUS, QE-EUS, and the combination of both for the differential diagnosis of SPT.
methodsSixty-two consecutive patients (mean age 64.3 years, range 32-89 years, 44 male) who underwent EUS for the evaluation of SPT were prospectively included. EUS was performed with a linear Pentax-EUS and a Hitachi-Preirus processor. The mass (area A) and a reference area B were selected during QE-EUS, and results expressed as B/A (strain ratio). A strain histogram of the mass was also evaluated. Microvascularization of the tumor was evaluated over 2 min during CEH-EUS after intravenous injection of 4.8 mL SonoVue. Final diagnosis was based on histopathology of surgical specimens or EUS-guided tissue acquisition and clinical follow-up in non-operated cases. Diagnostic accuracy of CEH-EUS, QE-EUS, and their combination was calculated.
resultsMedian size of the masses was 32 mm (range 12-111). Final diagnosis was pancreatic adenocarcinoma (
conclusionThe combination of QE-EUS and CEH-EUS is a useful tool for the differential diagnosis of SPT, giving complementary information. However, this combination does not significantly increase the diagnostic accuracy of either of the techniques performed alone.
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