Evidence map›Paper›PMID 28344778›Full record

ReviewF1000Research2017

Methodological advances in imaging intravital axonal transport.

James N Sleigh, Alessio Vagnoni, Alison E Twelvetrees, Giampietro Schiavo

Abstract readReview
In one paragraph

Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Neuronal signaling · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Imaging Intracellular Trafficking in Neurons of C. elegans.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  11. Long-distance regressive signaling in neural development and disease.Wiley interdisciplinary reviews. Developmental biology · 2021
    Review
  12. Finding order in slow axonal transport.Current opinion in neurobiology · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Axonal transport and neurological disease.Nature reviews. Neurology · 2019
    Review
  18. Defects in Axonal Transport in Inherited Neuropathies.Journal of neuromuscular diseases · 2019
    Review
  19. Review
  20. Zebrafish as a Model for the Study of LiveFrontiers in cell and developmental biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James N SleighSobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK.ORCID 0000-0002-3782-9045
Alessio VagnoniDivision of Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, UK; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Alison E TwelvetreesSobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK.
Giampietro SchiavoSobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK.ORCID 0000-0002-4319-8745

Funding

Medical Research Council MC_U105178790National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/N001753/1
6 · The paper itself

Abstract

Axonal transport is the active process whereby neurons transport cargoes such as organelles and proteins anterogradely from the cell body to the axon terminal and retrogradely in the opposite direction. Bi-directional transport in axons is absolutely essential for the functioning and survival of neurons and appears to be negatively impacted by both aging and diseases of the nervous system, such as Alzheimer's disease and amyotrophic lateral sclerosis. The movement of individual cargoes along axons has been studied

Indexed as

axonal transportintravital imagingneurons

Identifiers

PMID28344778
PMCPMC5333613

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.