Evidence map›Paper›PMID 28344572›Full record

ArticleFrontiers in microbiology2017

Gut Colonization by Methanogenic Archaea Is Associated with Organic Dairy Consumption in Children.

Jeroen A A van de Pol, Niels van Best, Catherine A Mbakwa, Carel Thijs, Paul H Savelkoul, Ilja C W Arts, Mathias W Hornef, Monique Mommers, John Penders

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  12. Gut Microbiome Changes in Anorexia Nervosa: A Comprehensive Review.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jeroen A A van de PolDepartment of Epidemiology, Care and Public Health Research Institute, Maastricht UniversityMaastricht, Netherlands; Department of Epidemiology, Grow - School for Oncology and Developmental Biology, Maastricht UniversityMaastricht, Netherlands.
Niels van BestDepartment of Medical Microbiology, School of Nutrition and Translational Research in Metabolism, Maastricht University Medical CentreMaastricht, Netherlands; Institute of Medical Microbiology, RWTH Aachen University HospitalAachen, Germany.
Catherine A MbakwaDepartment of Epidemiology, Care and Public Health Research Institute, Maastricht University Maastricht, Netherlands.
Carel ThijsDepartment of Epidemiology, Care and Public Health Research Institute, Maastricht University Maastricht, Netherlands.
Paul H SavelkoulDepartment of Medical Microbiology, School of Nutrition and Translational Research in Metabolism, Maastricht University Medical CentreMaastricht, Netherlands; Department of Medical Microbiology, Care and Public Health Research Institute, Maastricht University Medical CentreMaastricht, Netherlands.
Ilja C W ArtsMaastricht Centre for Systems Biology and Department of Epidemiology, School for Cardiovascular Diseases (CARIM), Maastricht University Maastricht, Netherlands.
Mathias W HornefInstitute of Medical Microbiology, RWTH Aachen University Hospital Aachen, Germany.
Monique MommersDepartment of Epidemiology, Care and Public Health Research Institute, Maastricht University Maastricht, Netherlands.
John PendersDepartment of Medical Microbiology, School of Nutrition and Translational Research in Metabolism, Maastricht University Medical CentreMaastricht, Netherlands; Department of Medical Microbiology, Care and Public Health Research Institute, Maastricht University Medical CentreMaastricht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota represents a complex and diverse ecosystem with a profound impact on human health, promoting immune maturation, and host metabolism as well as colonization resistance. Important members that have often been disregarded are the methanogenic archaea. Methanogenic archaea reduce hydrogen levels via the production of methane, thereby stimulating food fermentation by saccharolytic bacteria. On the other hand, colonization by archaea has been suggested to promote a number of gastrointestinal and metabolic diseases such as colorectal cancer, inflammatory bowel disease, and obesity. Archaea have been shown to be absent during infancy while omnipresent in school-aged children, suggesting that colonization may result from environmental exposure during childhood. The factors that determine the acquisition of methanogenic archaea, however, have remained undefined. Therefore, we aimed to explore determinants associated with the acquisition of the two main gastrointestinal archaeal species,

Indexed as

archaeachilddairy productsgutinfantmicrobiotamilkM. smithii

Identifiers

PMID28344572
PMCPMC5344914

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.