Evidence map›Paper›PMID 28344357›Full record

ArticleCoordination chemistry reviews2016

Quantum Dot Surface Engineering: Toward Inert Fluorophores with Compact Size and Bright, Stable Emission.

Sung Jun Lim, Liang Ma, André Schleife, Andrew M Smith

Open access · greenAbstract read
In one paragraph

Article in Coordination chemistry reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Deposition of CdSe Nanocrystals in Highly Porous SiOMaterials (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Antibody Self-Assembly Maximizes Cytoplasmic Immunostaining Accuracy of Compact Quantum Dots.Chemistry of materials : a publication of the American Chemical Society · 2021
    Article
  13. Article
  14. Foundations for Soft, Smart Matter by Active Mechanical Metamaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sung Jun LimMicro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA ; Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Liang MaMicro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA ; Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
André SchleifeDepartment of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Andrew M SmithMicro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA ; Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA ; Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
University of Illinois Urbana-Champaign · US

Funding

Research Training Program in Toxicology and Environmental HealthT32ES007326 · NIEHS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI Jodi A. Flaws · 2000 to 2026
$8.7M
Next-Generation Quantum Dots for Molecular and Cellular Imaging of CancerR00CA153914 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SMITH, ANDREW MICHAEL · 2012 to 2014
$709k
Small Quantum Dots for Super-Resolution of Neuronal Sub-Synaptic StructuresR21NS087413 · NINDS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SELVIN, PAUL R · 2014 to 2015
$402k
NCI NIH HHS R00 CA153914NIEHS NIH HHS T32 ES007326NINDS NIH HHS R21 NS087413
6 · The paper itself

Abstract

The surfaces of colloidal nanocrystals are complex interfaces between solid crystals, coordinating ligands, and liquid solutions. For fluorescent quantum dots, the properties of the surface vastly influence the efficiency of light emission, stability, and physical interactions, and thus determine their sensitivity and specificity when they are used to detect and image biological molecules. But after more than 30 years of study, the surfaces of quantum dots remain poorly understood and continue to be an important subject of both experimental and theoretical research. In this article, we review the physics and chemistry of quantum dot surfaces and describe approaches to engineer optimal fluorescent probes for applications in biomolecular imaging and sensing. We describe the structure and electronic properties of crystalline facets, the chemistry of ligand coordination, and the impact of ligands on optical properties. We further describe recent advances in compact coatings that have significantly improved their properties by providing small hydrodynamic size, high stability and fluorescence efficiency, and minimal nonspecific interactions with cells and biological molecules. While major progress has been made in both basic and applied research, many questions remain in the chemistry and physics of quantum dot surfaces that have hindered key breakthroughs to fully optimize their properties.

Indexed as

bioimagingCdSelabelligandsnanoparticleopticsphotoluminescenceprobesemiconductor

Identifiers

PMID28344357
PMCPMC5363762
OpenAlexW2336422404

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.