Evidence map›Paper›PMID 28344194›Full record

ArticleThe Journal of reproduction and development2017

An administration of TAK-683 at a minimally effective dose for luteinizing hormone stimulation under the absence of the ovary induces luteinizing hormone surge in ovary-intact goats.

Nahoko Kanai, Natsumi Endo, Satoshi Ohkura, Yoshihiro Wakabayashi, Hisanori Matsui, Hirokazu Matsumoto, Kaori Ishikawa, Akira Tanaka, Tatsuya Watanabe, Hiroaki Okamura and 1 more

Open access · goldAbstract read
In one paragraph

Article in The Journal of reproduction and development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Nahoko KanaiLaboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Natsumi EndoLaboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Satoshi OhkuraLaboratory of Animal Production Science, Nagoya University, Nagoya 464-8601, Japan.
Yoshihiro WakabayashiLaboratory of Neurobiology, National Institute of Agrobiological Sciences, Ibaraki 305-8602, Japan.
Hisanori MatsuiTakeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan.
Hirokazu MatsumotoTakeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan.
Kaori IshikawaTakeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan.
Akira TanakaTakeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan.
Tatsuya WatanabeTakeda Pharmaceutical Company Limited, Kanagawa 251-0012, Japan.
Hiroaki OkamuraLaboratory of Neurobiology, National Institute of Agrobiological Sciences, Ibaraki 305-8602, Japan.
Tomomi TanakaLaboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Takeda (Japan) · JPTokyo University of Agriculture and Technology · JPInstitute of Agrobiological Sciences · JPNagoya University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to evaluate hormonal responses and their association with the TAK-683 blood concentrations in goats administered TAK-683 at a low dose, which had been previously determined as the minimally effective dose for luteinizing hormone (LH) stimulation in ovariectomized goats. In Experiment 1, 5 µg of TAK-683 treatment had no significant stimulatory effect on LH secretion in ovariectomized Shiba goats (n = 4). In Experiment 2, cycling goats received the treatment of prostaglandin F

Indexed as

AnimalsFemaleGoatsKisspeptinsLuteinizing HormoneOvaryKisspeptinsLuteinizing HormoneTAK-683GoatsLuteinizing hormone (LH) surgeOvaryTAK-683

Identifiers

PMID28344194
PMCPMC5481633
OpenAlexW2602661200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.