ArticleInternational journal of cardiology2017
Isolated diastolic hypertension and incident heart failure in community-dwelling older adults: Insights from the Cardiovascular Health Study.
Article in International journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 27 citations in OpenAlex.
- Mortality trends in isolated systolic, diastolic, and combined hypertension: insights from NHANES database.Clinical hypertension · 2026Article
- Prevalence and Characteristics of Isolated Nighttime Masked Uncontrolled Hypertension in Treated Patients.Medicina (Kaunas, Lithuania) · 2024Article
- Leisure sedentary time and elevated blood pressure: evidence from the statutory retirement policy.Frontiers in public health · 2024Article
- Isolated Diastolic Hypertension and Risk of Cardiovascular Disease: Controversies in Hypertension-Con Side of the Argument.Hypertension (Dallas, Tex. : 1979) · 2022Article
- Blood pressure categorization and subclinical left ventricular dysfunction in antihypertensive medication-naive subjects.ESC heart failure · 2022Article
- Associations between triglyceride-glucose index and different hypertension subtypes: A population-based study in China.Frontiers in cardiovascular medicine · 2022Article
- Isolated diastolic hypertension and target organ damage: Findings from the STANISLAS cohort.Clinical cardiology · 2021Article
- The different risk factors for isolated diastolic hypertension and isolated systolic hypertension: a national survey.BMC public health · 2021Observational
- Association of Isolated Diastolic Hypertension Based on the Cutoff Value in the 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines With Subsequent Cardiovascular Events in the General Population.Journal of the American Heart Association · 2020Observational
- Relationship Between Ubiquitin-Specific Peptidase 18 and Hypertension in Polish Adult Male Subjects: A Cross-Sectional Pilot Study.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Article
- Prevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project.Journal of the American Heart Association · 2019Article
- Systolic-diastolic hypertension versus isolated systolic hypertension and incident heart failure in older adults: Insights from the Cardiovascular Health Study.International journal of cardiology · 2017Observational
- Isolated diastolic hypertension and its risk factors in semi-rural population of South India.Indian heart journalArticle
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Authors and funding
15 authors at 14 institutions in 4 countries.
Funding
Abstract
backgroundIsolated systolic hypertension and isolated diastolic hypotension are common in older adults and associated with a higher risk of incident heart failure (HF). However, little is known about the prevalence and impact of isolated diastolic hypertension in this population.
methodsIn the Cardiovascular Health Study (CHS), of the 5776 community-dwelling older adults ≥65years who had data on baseline systolic and diastolic blood pressure (SBP and DBP), 28 had isolated diastolic hypertension (DBP ≥90mmHg and SBP <140mmHg). From the 5748 without isolated diastolic hypertension, we excluded those with SBP ≥120mmHg (n=4451), DBP 80-89mmHg (n=20), DBP <60mmHg (n=425), normal BP taking anti-hypertensive medications (n=311), normal BP taking no anti-hypertensive medications but with history of hypertension (n=38), and baseline HF (n=5). The final cohort of 524 participants included 27 with isolated diastolic hypertension.
resultsPatients (n=524) had a mean (±SD) age of 71 (±5) years, 58% were women and 9% African American. There were no significant between-group age or sex differences; 37% of those with isolated diastolic hypertension (versus 7% without) were African American. Incident HF occurred in 19% and 7% of participants with and without isolated diastolic hypertension, respectively (multivariable-adjusted hazard ratio {HR}, 4.65; 95% confidence interval {CI}, 1.09-19.90; p=0.038). There was a trend toward higher cardiovascular mortality (HR, 4.59; 95% CI, 0.92-23.88; p=0.063).
conclusionAmong community-dwelling older adults, isolated diastolic hypertension is rare and is associated with higher risk for incident HF and cardiovascular mortality.
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