ReviewPsychological medicine2017
A trans-diagnostic perspective on obsessive-compulsive disorder.
Review in Psychological medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 161 citations in OpenAlex.
- A Systematic Review of Ecological Momentary Assessment for Obsessive-Compulsive Disorder.Journal of clinical psychology · 2026Pooled it
- Do You Match What I Match? A Systematic Review of Over 20 Years of the Emotional Face Matching Task Reveals Vast Inconsistencies in Design and Implementation.Human brain mapping · 2026Pooled it
- Inhibitory control in obsessive compulsive disorder: A systematic review and activation likelihood estimation meta-analysis of functional magnetic resonance imaging studies.NeuroImage. Clinical · 2022Pooled it
- Error Processing and Inhibitory Control in Obsessive-Compulsive Disorder: A Meta-analysis Using Statistical Parametric Maps.Biological psychiatry · 2019Pooled it
- A double-blind study assessing the impact of orbitofrontal theta burst stimulation on goal-directed behavior.Journal of psychopathology and clinical science · 2022Trial
- Non-invasive brain stimulation modulates neural correlates of performance monitoring in patients with obsessive-compulsive disorder.NeuroImage. Clinical · 2022Trial
- Efficacy and safety of transcranial direct current stimulation as an add-on treatment for obsessive-compulsive disorder: a randomized, sham-controlled trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Trial
- Obsessive-compulsive tendencies shift the balance between competitive neurocognitive functions.iScience · 2026Article
- Neural imbalance between feedback sensitivity and motor inhibition in compulsivity and negative urgency.Translational psychiatry · 2026Article
- Distinct cognitive and functional connectivity features from healthy cohorts can identify clinical obsessive-compulsive disorder.Molecular psychiatry · 2026Article
- Validation of the comprehensive online sleep monitoring scale in a large population sample.Frontiers in psychology · 2026Article
- A Multi-Symptom Circuit Architecture of Obsessive-Compulsive Disorder.medRxiv : the preprint server for health sciences · 2025Article
- Clinical characteristics and treatment response of a possible self-contamination subtype of obsessive-compulsive disorder: a prospective investigation.BMC psychiatry · 2025Article
- Metacognitive biases in anxiety-depression and compulsivity extend across perception and memory.PLOS mental health · 2025Article
- Implicit and explicit sense of agency in individuals with obsessive-compulsive tendencies.Frontiers in psychology · 2025Article
- Subjective Assessment of Rdoc-Related Constructs in Addiction and Compulsive Disorders: A Scoping Review.Clinical neuropsychiatry · 2024Review
- The association between salivary oxytocin, age, and puberty in children with and without OCD.Scientific reports · 2024Article
- Quantitative Expression of Latent Disease Factors in Individuals Associated with Psychopathology Dimensions and Treatment Response.Neuroscience bulletin · 2024Article
- Exploring latent clusters in pediatric OCD based on symptoms, severity, age, gender, and comorbidity.European child & adolescent psychiatry · 2024Article
- Heterogeneous appetite patterns in depression: computational modeling of nutritional interoception, reward processing, and decision-making.Frontiers in human neuroscience · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Progress in understanding the underlying neurobiology of obsessive-compulsive disorder (OCD) has stalled in part because of the considerable problem of heterogeneity within this diagnostic category, and homogeneity across other putatively discrete, diagnostic categories. As psychiatry begins to recognize the shortcomings of a purely symptom-based psychiatric nosology, new data-driven approaches have begun to be utilized with the goal of solving these problems: specifically, identifying trans-diagnostic aspects of clinical phenomenology based on their association with neurobiological processes. In this review, we describe key methodological approaches to understanding OCD from this perspective and highlight the candidate traits that have already been identified as a result of these early endeavours. We discuss how important inferences can be made from pre-existing case-control studies as well as showcasing newer methods that rely on large general population datasets to refine and validate psychiatric phenotypes. As exemplars, we take 'compulsivity' and 'anxiety', putatively trans-diagnostic symptom dimensions that are linked to well-defined neurobiological mechanisms, goal-directed learning and error-related negativity, respectively. We argue that the identification of biologically valid, more homogeneous, dimensions such as these provides renewed optimism for identifying reliable genetic contributions to OCD and other disorders, improving animal models and critically, provides a path towards a future of more targeted psychiatric treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.