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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2017

Health-related quality of life (HRQoL) and its correlates among community-recruited children living with HIV and uninfected children born to HIV-infected parents in West Bengal, India.

Aritra Das, Roger Detels, Abdelmonem A Afifi, Marjan Javanbakht, Frank J Sorvillo, Samiran Panda

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Aritra DasCARE India Solutions for Sustainable Development, H No. 14, Patliputra Colony, Patna, Bihar, 800013, India.
Roger DetelsDepartment of Epidemiology, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, 90095-1772, USA. detels@ucla.edu.
Abdelmonem A AfifiDepartment of Epidemiology, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, 90095-1772, USA.
Marjan JavanbakhtDepartment of Epidemiology, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, 90095-1772, USA.
Frank J SorvilloDepartment of Epidemiology, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, 90095-1772, USA.
Samiran PandaNational Institute of Cholera and Enteric Diseases (NICED/ICMR), P-33, CIT Road, Scheme-XM, Beliaghata, Kolkata, West Bengal, 700010, India.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAPHAEL J LANDOVITZ · 1997 to 2026
$53.5M
UCLA Fogarty AITRP-Supplement for North IndiaD43TW000013 · FIC · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DETELS, ROGER · 1988 to 2012
$14.6M
FIC NIH HHS D43 TW000013NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

purposeHelping children living with HIV (CLH) to attain an optimum quality of life is an important goal for HIV programs around the world. Our principal objectives were to determine the association of HIV infection with different domains of health-related quality of life (HRQoL) among 8- to 15-year-old CLH in India and to compare the HRQoL parameters between CLH and HIV-negative children born to HIV-infected parents ("HIV-affected"). We also assessed whether antiretroviral therapy (ART) and CD4 lymphocyte counts were associated with HRQoL among CLH.

methodsUsing the "Quality of Life (health-related) of Children Living with HIV/AIDS in India" instrument, we interviewed 199 CLH and 194 HIV-affected children from three districts of West Bengal, India. Participants were asked to quantify the difficulties faced by them in six HRQoL domains: physical, emotional, social, school functioning, symptoms, and discrimination.

resultsThe mean age of the participants was 11.6 (SD ± 2.5) years. CLH, compared to HIV-affected children, had poorer scores on all HRQoL domains except 'discrimination.' Among CLH, there were no significant differences in HRQoL domain scores (except in the 'discrimination' domain) between ART-treated and -untreated groups. CD4 lymphocyte count was found to be a significant positive predictor of the 'symptom' scale score.

conclusionsIn India, interventions for CLH mostly focus on biological disease. However, the current study revealed that HRQoL among CLH was much poorer than that of a socio-demographically comparable group. Culturally and developmentally appropriate psychosocial support measures for Indian CLH are urgently needed.

Indexed as

Sickness Impact ProfileAdolescentChildFemaleHIV InfectionsHumansIndiaMaleParentsReproducibility of ResultsChildrenHIVQuality of lifeReliabilityValidation study

Identifiers

PMID28343351
PMCPMC5511072

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.