ArticleNeuroImage2017
Hippocampal CA3-dentate gyrus volume uniquely linked to improvement in associative memory from childhood to adulthood.
Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Meta-Analysis of Hippocampal Volume and Episodic Memory in Preterm and Term Born Individuals.Neuropsychology review · 2024Pooled it
- Age-related differences in hippocampal subfield volumes across the human lifespan: A meta-analysis.Hippocampus · 2023Pooled it
- A meta-analysis of the relation between hippocampal volume and memory ability in typically developing children and adolescents.Hippocampus · 2022Pooled it
- Distinct spatial associations of adversity with hippocampal macro- and microstructure in early adolescence.bioRxiv : the preprint server for biology · 2026Article
- Age-related volumetric differences of hippocampal subfields in the developing brain: a retrospective MRI study.Brain structure & function · 2026Article
- Brain mechanical properties predict longitudinal cognitive change in aging and Alzheimer's disease.Neurobiology of aging · 2025Article
- Reinstatement and transformation of memory traces for recognition.Science advances · 2025Article
- SpatialPrompt: spatially aware scalable and accurate tool for spot deconvolution and domain identification in spatial transcriptomics.Communications biology · 2024Article
- Asynchronous development of memory integration and differentiation influences temporal memory organization.Developmental science · 2024Article
- KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development.Brain structure & function · 2024Article
- Development of human hippocampal subfield microstructure and relation to associative inference.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Household socioeconomic status relates to specific hippocampal subfield volumes across development.Hippocampus · 2023Article
- Development of the neural correlates of recollection.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Differential effects of emotional valence on mnemonic performance with greater hippocampal maturity.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- Volumetric differences in hippocampal subfields and associations with clinical measures in myalgic encephalomyelitis/chronic fatigue syndrome.Journal of neuroscience research · 2022Article
- Intraobject and extraobject memory binding across early development.Developmental psychology · 2022Article
- Developmental differences in memory reactivation relate to encoding and inference in the human brain.Nature human behaviour · 2022Article
- Differential associations of visual memory with hippocampal subfields in subjective cognitive decline and amnestic mild cognitive impairment.BMC geriatrics · 2022Article
- Test-retest reliability of hippocampal subfield volumes in a developmental sample: Implications for longitudinal developmental studies.Journal of neuroscience research · 2021Article
- Longitudinal indices of human cognition and brain structure.Journal of neuroscience research · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Associative memory develops into adulthood and critically depends on the hippocampus. The hippocampus is a complex structure composed of subfields that are functionally-distinct, and anterior-posterior divisions along the length of the hippocampal horizontal axis that may also differ by cognitive correlates. Although each of these aspects has been considered independently, here we evaluate their relative contributions as correlates of age-related improvement in memory. Volumes of hippocampal subfields (subiculum, CA1-2, CA3-dentate gyrus) and anterior-posterior divisions (hippocampal head, body, tail) were manually segmented from high-resolution images in a sample of healthy participants (age 8-25 years). Adults had smaller CA3-dentate gyrus volume as compared to children, which accounted for 67% of the indirect effect of age predicting better associative memory via hippocampal volumes. Whereas hippocampal body volume demonstrated non-linear age differences, larger hippocampal body volume was weakly related to better associative memory only when accounting for the mutual correlation with subfields measured within that region. Thus, typical development of associative memory was largely explained by age-related differences in CA3-dentate gyrus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.