Evidence map›Paper›PMID 28342809›Full record

ArticleBiochimica et biophysica acta. Bioenergetics2017

Identity and function of a cardiac mitochondrial small conductance Ca

MeiYing Yang, Amadou K S Camara, Mohammed Aldakkak, Wai-Meng Kwok, David F Stowe

Open access · greenAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Bioenergetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Small-conductance CaThe Journal of physiology · 2026
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  6. Small-conductance calcium-activated potassium channels in the heart: expression, regulation and pathological implications.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
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  14. The Genetic Puzzle of Familial Atrial Fibrillation.Frontiers in cardiovascular medicine · 2020
    Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

MeiYing YangDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Amadou K S CamaraDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA.
Mohammed AldakkakDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA.
Wai-Meng KwokDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI, USA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA.
David F StoweDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Biomedical Engineering, Medical College of Wisconsin and Marquette University, Milwaukee, WI, USA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA; Research Service, Zablocki VA Medical Center, Milwaukee, WI, USA. Electronic address: dfstowe@mcw.edu.
Medical College of Wisconsin · USMarquette University · US

Funding

Stem Cell CoreP01GM066730 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI DASH, RANJAN K · 2003 to 2019
$23.6M
INTERACTION BETWEEN ANESTHETICS AND CALCIUM ANTAGONISTSR01HL034708 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI BOSNJAK, ZELJKO J. · 1986 to 2013
$3.9M
Mitochondrial Ca-sensitive K channel-induced superoxide and cardiac protectionR01HL089514 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI STOWE, DAVID F · 2009 to 2012
$1.4M
Differential cardioprotection by mitochondrial Ca2+ sensitive potassium channelsI01BX002539 · VA · CLEMENT J. ZABLOCKI VA MEDICAL CENTER · PI STOWE, DAVID F · 2016 to 2019
–
BLRD VA I01 BX002539NHLBI NIH HHS R01 HL034708NHLBI NIH HHS R01 HL089514NIGMS NIH HHS P01 GM066730
6 · The paper itself

Abstract

We provide evidence for location and function of a small conductance, Ca

Indexed as

1-NaphthylamineAmino Acid SequenceAnimalsBenzimidazolesCalcium ChlorideCell HypoxiaCell LineGuinea PigsHumansMembrane Potential, MitochondrialMiceMitochondria, HeartMyocardial Reperfusion InjuryMyocytes, CardiacPotassiumPotassium Channel Blockers1-Naphthylamine5,6-dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-oneBenzimidazolesCalcium ChlorideKCNN3 protein, humanKcnn3 protein, ratPotassiumPotassium Channel BlockersProtein IsoformsRecombinant Fusion ProteinsRNA, Messenger(R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamineSmall-Conductance Calcium-Activated Potassium ChannelsCardiac mitochondriaCell signalingInner mitochondrial membraneIschemia reperfusion injuryOxidant stressSmall conductance Ca(2+)-sensitive K(+) channel

Identifiers

PMID28342809
PMCPMC5749404
OpenAlexW2598599915

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.