ArticlePreventive medicine2017
The association of dietary inflammatory potential with depression and mental well-being among U.S. adults.
Article in Preventive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 8 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- Nonlinear dose-response relationship between dietary inflammatory index and risk of depression: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Dietary inflammatory potential and the incidence of depression and anxiety: a meta-analysis.Journal of health, population, and nutrition · 2022Pooled it
- Dietary Inflammatory Index in relation to Type 2 Diabetes: A Meta-Analysis.International journal of clinical practice · 2022Pooled it
- Understanding the relationship between type 2 diabetes and depression: lessons from genetically informative study designs.Diabetic medicine : a journal of the British Diabetic Association · 2021Pooled it
- Association Between Dietary Inflammatory Index and Mental Health: A Systematic Review and Dose-Response Meta-Analysis.Frontiers in nutrition · 2021Pooled it
- Evidence of the Importance of Dietary Habits Regarding Depressive Symptoms and Depression.International journal of environmental research and public health · 2020Pooled it
- Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies.Molecular psychiatry · 2019Pooled it
- Dietary Inflammatory Potential and the Risk of Incident Depression in Adults: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2019Pooled it
- Impact of Edible Cricket Consumption on Gut Microbiota in Healthy Adults, a Double-blind, Randomized Crossover Trial.Scientific reports · 2018Trial
- Association between dietary inflammatory index and depression in individuals with cardiovascular-kidney-metabolic syndrome stage 0-3: a cross-sectional study.Diabetology & metabolic syndrome · 2026Article
- Neuroinflammation and treatment resistance in major depressive disorder.Frontiers in pharmacology · 2026Review
- Associations of Sleep Quality with Cognitive Function in Chinese Older Adults: The Roles of Self-Efficacy and Depressive Symptoms.Clinical interventions in aging · 2026Article
- Inflammatory potential of the diet and self-rated quality of life in Italian adults.Frontiers in nutrition · 2026Article
- Associations of Dietary Inflammatory and Antioxidant Indices with Mental Health Indicators Among University Students: A Cross-Sectional Study.Nutrients · 2025Article
- Burnout Risk Profiles in Psychology Students: An Exploratory Study with Machine Learning.Behavioral sciences (Basel, Switzerland) · 2025Article
- Effects of the Energy-Adjusted Dietary Inflammation Index During Pregnancy on Prenatal Depression: The Mediating Effect of Sleep Quality.Nutrients · 2025Article
- L-shaped association of dietary inflammatory index (DII) and chronic diarrhea: results from NHANES 2005-2010.BMC public health · 2025Article
- Associations between the Dietary Inflammatory Index and depression among pregnant and postpartum women: analysis of NHANES 2005-2018.Frontiers in nutrition · 2025Article
- Association of dietary inflammatory index with liver fibrosis and fatty liver index in a population with metabolic dysfunction-associated steatotic liver disease: A cross-sectional study.Frontiers in nutrition · 2025Article
- The impact of mental health literacy on depression, anxiety and well-being among vocational nursing students: mediating roles of resilience.Frontiers in psychiatry · 2025Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Current treatment for depression is not considered effective among all cases and, thus far, nutritional protocols are minimal within depression treatment guidelines. Recently, there has been increasing interest in a possible protective and modifiable role of diet in common mental disorders, including depression, due to pro- and anti-inflammatory properties of nutrients. This study aims to investigate whether the Dietary Inflammatory Index (DII), designed to estimate the inflammatory potential of diet, is associated with depression and other measures of mental health. In a representative sample of U.S. adults (≥20years of age, N=11,592), the distribution of DII score is assessed. Multivariate logistic regression models determine the association between DII quintile and depression. Associations of DII quintile with frequent distress and frequent anxiety are also evaluated. In fully adjusted models, higher DII score is associated with over a two-fold higher odds of depression (OR (95% CI)=2.26 (1.60, 3.20) for highest vs. lowest quintile, Type III p-value≤0.0001). DII score is also associated with higher odds of frequent distress (OR (95% CI)=1.81 (1.20, 2.71) for highest vs. lowest quintile, Type III p-value=0.0167). This association was not significant for frequent anxiety (Type III p-value=0.12). Results of this study indicate that dietary inflammatory potential is associated with depression. These results are consistent with existing hypotheses that inflammatory pathways play a role in the etiology of depression. Further research examining the underlying biological and cellular mechanisms of depression is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.