Evidence map›Paper›PMID 28342387›Full record

ArticleVirology2017

Isolation and characterization of a novel putative human polyomavirus.

Tarik Gheit, Sankhadeep Dutta, Javier Oliver, Alexis Robitaille, Shalaka Hampras, Jean-Damien Combes, Sandrine McKay-Chopin, Florence Le Calvez-Kelm, Neil Fenske, Basil Cherpelis and 5 more

Open access · greenAbstract read
In one paragraph

Article in Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 96 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Mapping of Human Polyomavirus in Renal Cell Carcinoma Tissues.International journal of molecular sciences · 2024
    Article
  6. Review
  7. Genetic characterization of Sus scrofa papillomavirus type 1 from domestic pigs in Guangxi Province, China.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. [Human polyomavirus-associated skin diseases].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Tarik GheitInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
Sankhadeep DuttaInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
Javier OliverInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
Alexis RobitailleInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
Shalaka HamprasDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA.
Jean-Damien CombesInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
Sandrine McKay-ChopinInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
Florence Le Calvez-KelmInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
Neil FenskeDepartment of Dermatology & Cutaneous Surgery, University of South Florida, Morsani College of Medicine, Tampa, FL, USA; Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Basil CherpelisDepartment of Dermatology & Cutaneous Surgery, University of South Florida, Morsani College of Medicine, Tampa, FL, USA; Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Anna R GiulianoCenter for Infection Research in Cancer, Moffitt Cancer Center, Tampa, FL, USA.
Silvia FranceschiInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
James McKayInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France.
Dana E RollisonDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA.
Massimo TommasinoInternational Agency for Research on Cancer, World Health Organization, Lyon 69372, France. Electronic address: icb@iarc.fr.
Centre international de recherche sur le cancer · FRMoffitt Cancer Center · USUniversity of South Florida · US

Funding

Prospective study of cutaneous viral infections and non-melanoma skin cancerR01CA177586 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI ROLLISON, DANA ELISE · 2014 to 2018
$3.4M
NCI NIH HHS R01 CA177586World Health Organization 001
6 · The paper itself

Abstract

The small double-stranded DNA polyomaviruses (PyVs) form a family of 73 species, whose natural hosts are primarily mammals and birds. So far, 13 PyVs have been isolated in humans, and some of them have clearly been associated with several diseases, including cancer. In this study, we describe the isolation of a novel PyV in human skin using a sensitive degenerate PCR protocol combined with next-generation sequencing. The new virus, named Lyon IARC PyV (LIPyV), has a circular genome of 5269 nucleotides. Phylogenetic analyses showed that LIPyV is related to the raccoon PyV identified in neuroglial tumours in free-ranging raccoons. Analysis of human specimens from cancer-free individuals showed that 9 skin swabs (9/445; 2.0%), 3 oral gargles (3/140; 2.1%), and one eyebrow hair sample (1/439; 0.2%) tested positive for LIPyV. Future biological and epidemiological studies are needed to confirm the human tropism and provide insights into its biological properties.

Indexed as

Amino Acid SequenceAnimalsGenome, ViralGliomaHumansMolecular Sequence DataPhylogenyPolyomavirusPolyomavirus InfectionsRaccoonsViral ProteinsViral ProteinsHumanNew polyomavirusSkin

Identifiers

PMID28342387
PMCPMC9265179
OpenAlexW2598454049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.