Evidence map›Paper›PMID 28342273›Full record

Trial reportClinical transplantation2017

Characteristics of compatible pair participants in kidney paired donation at a single center.

Francis L Weng, Tracy Grogan, Anup M Patel, Shamkant Mulgaonkar, Marie M Morgievich

Abstract readClinical Trial
In one paragraph

Trial report in Clinical transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Living donor kidney paired exchange: An observational study.Annals of medicine and surgery (2012) · 2022
    Article
  5. Motivations and outcomes of compatible living donor-recipient pairs in paired exchange.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francis L WengRenal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ, USA.ORCID 0000-0001-9780-4803
Tracy GroganRenal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ, USA.
Anup M PatelRenal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ, USA.
Shamkant MulgaonkarRenal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ, USA.
Marie M MorgievichRenal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ, USA.

Funding

Modifiable factors affecting racial disparities in live kidney donationR01MD007664 · NIMHD · ST. BARNABAS MEDICAL CENTER · PI WATERMAN, AMY DOGGETTE, WENG, FRANCIS L · 2014 to 2018
$1.7M
Increasing live donor kidney transplant among Blacks on the transplant waitlistR01DK098744 · NIDDK · ST. BARNABAS MEDICAL CENTER · PI WENG, FRANCIS L · 2012 to 2016
$994k
NIDDK NIH HHS R01 DK098744NIMHD NIH HHS R01 MD007664
6 · The paper itself

Abstract

Compatible pairs of living kidney donors and their intended recipients can enter into kidney paired donation (KPD) and facilitate additional living donor kidney transplants (LDKTs). We examined 11 compatible pairs (the intended recipients and their intended, compatible donors) who participated in KPD, along with the recipients' 11 matched, exchange donors. The 11 pairs participated in 10 separate exchanges (three were multicenter exchanges) that included 33 total LDKTs (22 additional LDKTs). All the intended donors were blood group O and female, with a mean living kidney donor profile index (LKDPI) of 27.6 (SD 16.8). The matched donors had a mean LKDPI of 9.4 (SD 31.7). Compatible pairs entered KPD for altruistic reasons (N=2) or due to mismatch of age (N=7) or body/kidney size (N=2) between the recipient and intended donor. In four cases, retrospective calculation of the LKDPI revealed that the matched donor had a higher LKDPI than the intended donor. Of the 22 recipients of LDKTs enabled by the compatible pairs, three were highly sensitized, with PRA >80%. In conclusion, most compatible pairs entered into KPD so that the recipient could receive a LDKT transplant from a donor whose age or body/kidney size were more favorable to post-transplant outcomes.

Indexed as

HistocompatibilityTissue and Organ ProcurementAdultAgedDonor SelectionFemaleFollow-Up StudiesGlomerular Filtration RateHumansKidney Failure, ChronicKidney Function TestsKidney TransplantationLiving DonorsMaleMiddle AgedPrognosisblood group incompatibilityhistocompatibilitykidney transplantliving donorspaired donationpatient selection

Identifiers

PMID28342273
PMCPMC5831242

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.