Evidence map›Paper›PMID 28342224›Full record

ArticleImmunology2017

Interleukin-18 activates Vγ9Vδ2

Alanna S Murday, Suchita Chaudhry, C David Pauza

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  7. Protective Role ofJournal of immunology research · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Alanna S MurdayInstitute of Human Virology and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Suchita ChaudhryInstitute of Human Virology and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
C David PauzaInstitute of Human Virology and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-0559-793X
University of Maryland, Baltimore · US

Funding

HIV Persistence and Cardiopulmonary DiseaseR21HL126533 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI SALVATO, MARIA S. · 2015 to 2016
$424k
Vgamma2Vdelta2 T cell recognition of HIV-infected cells in the lungF31HL128159 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MURDAY, ALANNA · 2015 to 2016
$54k
NHLBI NIH HHS F31 HL128159NHLBI NIH HHS R21 HL126533
6 · The paper itself

Abstract

The study aimed to identify an immunoregulatory factor that restores the phosphoantigen response of Vγ9Vδ2

Indexed as

AntigensCell ProliferationCells, CulturedDiphosphonatesHemiterpenesHIV-1HIV InfectionsHumansImidazolesImmunologic MemoryImmunophenotypingImmunotherapyInterleukin-18Killer Cells, NaturalLymphocyte ActivationOrganophosphorus CompoundsAntigensDiphosphonatesHemiterpenesImidazolesInterleukin-18isopentenyl pyrophosphateOrganophosphorus CompoundsReceptors, Antigen, T-Cell, gamma-deltaT-cell receptor Vdelta2, humanT-cell receptor Vgamma9, humanZoledronic Acidhuman immunodeficiency virusinflammasomeinterleukin-18phosphoantigenVγ9Vδ2γδ T cell

Identifiers

PMID28342224
PMCPMC5506445
OpenAlexW2599004430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.