ArticlePsychopharmacology2017
Evaluation of structural connectivity changes in betel-quid chewers using generalized q-sampling MRI.
Article in Psychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Article
- Assessment of disrupted brain functional connectome in tuberous sclerosis complex using resting-state fMRI.Medicine · 2022Article
- Mapping white matter structural and network alterations in betel quid-dependent chewers using high angular resolution diffusion imaging.Frontiers in psychiatry · 2022Article
- Disrupted white matter connectivity and organization of brain structural connectomes in tuberous sclerosis complex patients with neuropsychiatric disorders using diffusion tensor imaging.Magma (New York, N.Y.) · 2021Article
- Reduced Cortical Thickness in the Right Caudal Middle Frontal Is Associated With Symptom Severity in Betel Quid-Dependent Chewers.Frontiers in psychiatry · 2020Article
- Structural and Functional Alterations in Betel-Quid Chewers: A Systematic Review of Neuroimaging Findings.Frontiers in psychiatry · 2019Article
- Brain structural networks and connectomes: the brain-obesity interface and its impact on mental health.Neuropsychiatric disease and treatment · 2018Article
- Altered Gray-Matter Volumes Associated With Betel Quid Dependence.Frontiers in psychiatry · 2017Article
- Altered Brain Functional Connectivity in Betel Quid-Dependent Chewers.Frontiers in psychiatry · 2017Article
- White Matter Integrity Deficit Associated with Betel Quid Dependence.Frontiers in psychiatry · 2017Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleBetel quid (BQ) is a common addictive substance in many Asian countries. However, few studies have focused on the influences of BQ on the brain. It remains unclear how BQ can affect structural brain abnormalities in BQ chewers.
objectivesWe aimed to use generalized q-sampling imaging (GQI) to evaluate the impact of the neurological structure of white matter caused by BQ.
methodsThe study population comprised 16 BQ chewers, 15 tobacco and alcohol controls, and 17 healthy controls. We used GQI with voxel-based statistical analysis (VBA) to evaluate structural brain and connectivity abnormalities in the BQ chewers compared to the tobacco and alcohol controls and the healthy controls. Graph theoretical analysis (GTA) and network-based statistical (NBS) analysis were also performed to identify the structural network differences among the three groups.
resultsUsing GQI, we found increases in diffusion anisotropy in the right anterior cingulate cortex (ACC), the midbrain, the bilateral angular gyrus, the right superior temporal gyrus (rSTG), the bilateral superior occipital gyrus, the left middle occipital gyrus, the bilateral superior and inferior parietal lobule, and the bilateral postcentral and precentral gyrus in the BQ chewers when compared to the tobacco and alcohol controls and the healthy controls. In GTA and NBS analyses, we found more connections in connectivity among the BQ chewers, particularly in the bilateral anterior cingulum.
conclusionsOur results provided further evidence indicating that BQ chewing may lead to brain structure and connectivity changes in BQ chewers.
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