Trial reportLasers in medical science2017
The effect of LED on blood microcirculation during chronic wound healing in diabetic and non-diabetic patients-a prospective, double-blind randomized study.
Trial report in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Clinical dosimetry and efficacy of LED photobiomodulation for chronic lower-limb wound healing: a systematic review of randomized trials.Lasers in medical science · 2026Pooled it
- Pooled it
- Effects of low-level light therapy on xerostomia related to hyposalivation: a systematic review and meta-analysis of clinical trials.Lasers in medical science · 2022Pooled it
- Photobiomodulation: systematic review and meta-analysis of the most used parameters in the resolution diabetic foot ulcers.Lasers in medical science · 2021Pooled it
- The impact of photobiomodulation of major salivary glands on caries risk.Lasers in medical science · 2020Trial
- Evaluation of the therapeutic effects of led (λ627 ± 10 nm) on the initial phase of ankle sprain treatment: a randomised placebo-controlled clinical trial.Lasers in medical science · 2018Trial
- Photobiomodulation combined with dynamic thermal imaging as a diagnostic tool for chronic leg ulcers.Lasers in medical science · 2026Article
- Application of photobiomodulation therapy by LED using a combined red and near-infrared light spectrum improves the vascular function of the radial artery in vitro.Lasers in medical science · 2025Article
- The synergistic effect of photobiomodulation, methylglyoxal, and complex magnetic fields on human dermal fibroblasts: potential applications for chronic wound treatments.Lasers in medical science · 2025Article
- A Natural Latex-Based Smart Dressing for Curcumin Delivery Combined with LED Phototherapy in Diabetic Foot Ulcers: A Pilot Clinical Study.Pharmaceutics · 2025Article
- [Expert consensus on systematic assessment and treatment of refractory wounds in the elderly (2025 edition)].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025Article
- Assessment of photobiomodulation in response to the microcirculation in arteriovenous fistula for hemodialysis patient.Asian biomedicine : research, reviews and news · 2025Article
- Efficacy of Photobiomodulation in Reducing Symptomatology and Improving the Quality of Life in Patients with Xerostomia and Hyposalivation: A Randomized Controlled Trial.Journal of clinical medicine · 2022Article
- New evidence from hyperspectral imaging analysis on the effect of photobiomodulation therapy on normal skin oxygenation.Lasers in medical science · 2022Article
- Effect of 660/850 nm LED on the microcirculation of the foot: neurovascular biphasic reflex.Lasers in medical science · 2021Article
- Fluorescent Light Energy and Chronic Lesions: A Winning Association.Plastic and reconstructive surgery. Global open · 2021Article
- The Path to an Evidence-Based Treatment Protocol for Extraoral Photobiomodulation Therapy for the Prevention of Oral Mucositis.Frontiers in oral health · 2021Review
- Measurement of Physical Parameters and Development of a Light Emitting Diodes Device for Therapeutic Use.Journal of medical systems · 2020Article
- Low-Level Laser Therapy for Diabetic Dermopathy in Patients With Type 2 Diabetes: A Placebo-Controlled Pilot Study.Journal of lasers in medical sciences · 2020Article
- Light-emitting diodes in dermatology: A systematic review of randomized controlled trials.Lasers in surgery and medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic wounds, especially in diabetic patients, represent a challenging health issue. Since standard treatment protocols often do not provide satisfactory results, additional treatment methods-like phototherapy using low-level light therapy-are being investigated. The aim of our study was to evaluate the effect of phototherapy with light-emitting diodes on chronic wound treatment in diabetic and non-diabetic patients. Since a sufficient blood supply is mandatory for wound healing, the evaluation of microcirculation in the healthy skin at a wound's edge was the main outcome measure. Forty non-diabetic patients and 39 diabetics with lower limb chronic wounds who were referred to the University Medical Center Ljubljana between October 2012 and June 2014 were randomized to the treated and control groups. The treated group received phototherapy with LED 2.4 J/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.