Evidence map›Paper›PMID 28341674›Full record

ArticleApplied and environmental microbiology2017

Interbacterial Adhesion Networks within Early Oral Biofilms of Single Human Hosts.

Robert J Palmer, Nehal Shah, Alex Valm, Bruce Paster, Floyd Dewhirst, Taichi Inui, John O Cisar

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01712672 (Bacterial Arrangement in Supragingival Biofilms), which is not on this map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01712672 completednot on this map

Bacterial Arrangement in Supragingival Biofilms

TypeobservationalSponsorNational Institute of Dental and Craniofacial Research (NIDCR)Ran2013 to 2016Enrolled15ConditionsDental Plaque, Oral Health, Periodontal Disease and Caries, Periodontal Disease
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 64 citations in OpenAlex.

  1. Trial
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  11. Improved Visualization of Oral Microbial Consortia.Journal of dental research · 2024
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Comparative genomics ofMicrobial genomics · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Robert J PalmerNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA rjpalmer@nih.gov.
Nehal ShahNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA.
Alex ValmEunice Kennedy Shriver National Center for Child Health and Development, National Institutes of Health, Bethesda, Maryland, USA.
Bruce PasterForsyth Institute, Cambridge, Massachusetts, USA, and Harvard School of Dental Medicine, Boston, Massachusetts, USA.
Floyd DewhirstForsyth Institute, Cambridge, Massachusetts, USA, and Harvard School of Dental Medicine, Boston, Massachusetts, USA.
Taichi InuiWrigley, Chicago, Illinois, USA.
John O CisarNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA.
National Institute of Dental and Craniofacial Research · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

Mouse Oral Microbiome DatabaseR37DE016937 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI DEWHIRST, FLOYD E · 2011 to 2020
$8.6M
Cultivation, Nature, Ecology and Pathogenicity of the Uncultivable Oral MicrobiomR01DE024468 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI ALM, ERIC JOHN, DEWHIRST, FLOYD E · 2014 to 2018
$7.3M
NIDCR NIH HHS R37 DE016937
6 · The paper itself

Abstract

Specific interbacterial adhesion, termed coaggregation, is well established for three early colonizers of the plaque biofilm: streptococci, actinomyces, and veillonellae. However, little is known about interactions of other early colonizers and about the extent of interactions within the bacterial community from a single host. To address these gaps, subject-specific culture collections from two individuals were established using an intraoral biofilm retrieval device. Molecular taxonomy (Human Oral Microbe Identification Microarray [HOMIM]) analysis of biofilm samples confirmed the integrity and completeness of the collections. HOMIM analysis verified the isolation of

Indexed as

Bacterial AdhesionBacterial Physiological PhenomenaBiofilmsAdultBacteriaDental PlaqueHumansMaleMiddle AgedbiofilmscoaggregationHaemophilusoral microbiomeRothiastreptococci

Identifiers

PMID28341674
PMCPMC5440702
OpenAlexW2602516577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.