Evidence map›Paper›PMID 28341634›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2017

Contribution of two-pore K

Sam Chai, Xiaoping Wan, Drew M Nassal, Haiyan Liu, Christine S Moravec, Angelina Ramirez-Navarro, Isabelle Deschênes

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Cardiac Manifestations ofHealth science reports · 2026
    Review
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  3. Article
  4. Review
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  6. Review
  7. Article
  8. Review
  9. Article
  10. Cardiovascular pharmacology of KNaunyn-Schmiedeberg's archives of pharmacology · 2018
    Article
  11. Statistical considerations in reporting cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sam ChaiDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio.
Xiaoping WanHeart and Vascular Research Center, Department of Medicine, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio; and.
Drew M NassalDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio.
Haiyan LiuHeart and Vascular Research Center, Department of Medicine, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio; and.
Christine S MoravecDepartment of Molecular Cardiology, Cleveland Clinic, Cleveland, Ohio.
Angelina Ramirez-NavarroHeart and Vascular Research Center, Department of Medicine, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio; and.
Isabelle DeschênesDepartment of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio; isabelle.deschenes@case.edu.ORCID http://orcid.org/0000-0002-1812-7267
MetroHealth Medical Center · USCleveland Clinic · US

Funding

Genotype-Phenotype Discordance in Long QT SyndromeR01HL124245 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI DESCHENES, ISABELLE · 2014 to 2017
$2.2M
NHLBI NIH HHS R01 HL124245
6 · The paper itself

Abstract

Two-pore K

Indexed as

Action PotentialsCell DifferentiationArrhythmias, CardiacCase-Control StudiesCell LineFemaleGene Expression ProfilingHeart FailureHeart VentriclesHumansInduced Pluripotent Stem CellsMaleMyocardial IschemiaMyocytes, CardiacPotassium Channels, Tandem Pore DomainReal-Time Polymerase Chain ReactionPotassium Channels, Tandem Pore Domainaction potential durationcardiac repolarizationheart failureinduced pluripotent stem cell-derived cardiomyocytestwo-pore potassium channels

Identifiers

PMID28341634
PMCPMC5495933
OpenAlexW2599685335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.