ArticleRespiratory medicine2017
Association of systemic inflammation, adiposity, and metabolic dysregulation with asthma burden among Hispanic adults.
Article in Respiratory medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Association of Metformin Use with Asthma Exacerbation in Patients with Concurrent Asthma and Diabetes: A Systematic Review and Meta-Analysis of Observational Studies.Canadian respiratory journal · 2020 · on this mapPooled it
- Metformin for asthma exacerbations.The Cochrane database of systematic reviews · 2026Article
- Associations between C-reactive protein-triglyceride glucose index and asthma risk among Chinese adults: evidence from the CHARLS cohort and external hospital-based validation.Frontiers in immunology · 2026Article
- Association of High-Sensitivity C-Reactive Protein Levels with Proximal Airway CT Morphology in Obesity.Obesity surgery · 2025Article
- Impact of metabolic and weight components on incident asthma using a real-world cohort.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024Article
- Asthmatic patients with high serum amyloid A have proinflammatory HDL: Implications for augmented systemic and airway inflammation.The Journal of allergy and clinical immunology · 2024Article
- Application of Metabolomics in Obesity-Related Childhood Asthma Subtyping: A Narrative Scoping Review.Metabolites · 2023Article
- Endotyping pediatric obesity-related asthma: Contribution of anthropometrics, metabolism, nutrients, and CD4The Journal of allergy and clinical immunology · 2022Article
- Racial/ethnic disparities on inflammation and response to methylprednisolone in severe COVID-19 pneumonia.BMC infectious diseases · 2022Article
- Preliminary development of a questionnaire to measure the extra-pulmonary symptoms of severe asthma.BMC pulmonary medicine · 2021Article
- The Gut/Lung Microbiome Axis in Obesity, Asthma, and Bariatric Surgery: A Literature Review.Obesity (Silver Spring, Md.) · 2021Review
- High-Density Lipoprotein (HDL) in Allergy and Skin Diseases: Focus on Immunomodulating Functions.Biomedicines · 2020Review
- Impact of a natural disaster on access to care and biopsychosocial outcomes among Hispanic/Latino cancer survivors.Scientific reports · 2020Article
- Extracorporeal and advanced therapies for progressive refractory near-fatal acute severe asthma in children.Pediatric pulmonology · 2020Review
- Obesity Does Not Increase the Risk of Asthma Readmissions.Journal of clinical medicine · 2020Article
- Association of Metformin Initiation and Risk of Asthma Exacerbation. A Claims-based Cohort Study.Annals of the American Thoracic Society · 2019Article
- [Association of blood lipids with childhood asthma].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
- Adiposity and Asthma in a Nationwide Study of Children and Adults in the United States.Annals of the American Thoracic Society · 2018Article
Corrections and comments
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Authors and funding
14 authors at 9 institutions in 1 country.
Funding
Abstract
rationaleObesity-related asthma is associated with higher disease burden than normal-weight asthma among Hispanics. Adiposity, metabolic dysregulation, and inflammation are all implicated in pathogenesis of obesity-related asthma, but their independent contributions are poorly understood.
objectiveTo examine the independent contributions of body fat distribution, metabolic abnormalities and inflammation on asthma symptoms and pulmonary function among Hispanics.
methodsParticipants of the Hispanic Community Health Study/Study of Latinos with doctor-diagnosed asthma who completed an asthma symptom questionnaire and performed a valid spirometry were included in the analysis (n = 1126). Multivariate analysis was used to examine the independent association of general adiposity (assessed using body mass index), truncal adiposity (assessed by waist circumference), metabolic dysregulation (presence of insulin resistance and low HDL) and inflammation (high-sensitivity C-Reactive Protein≥3 mg/L) with reported asthma symptoms or pulmonary function measures (FEV
resultsOf the 1126 participants, 334 (29.5%) were overweight, and 648 (57.8%) were obese. FEV
conclusionsOur findings suggest that hs-CRP and low HDL, rather than general and truncal adiposity, are associated with asthma burden among overweight and obese Hispanic adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.