Evidence map›Paper›PMID 28340519›Full record

ArticleThe Journal of comparative neurology2017

Barrington's nucleus: Neuroanatomic landscape of the mouse "pontine micturition center".

Anne M J Verstegen, Veronique Vanderhorst, Paul A Gray, Mark L Zeidel, Joel C Geerling

Open access · greenAbstract read
In one paragraph

Article in The Journal of comparative neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. Article
  3. Intersectional expression ofAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. AAV-PHP.eB Peripheral Delivery and Central Expression in Cre Mice.The Journal of comparative neurology · 2026
    Article
  9. Article
  10. From bladder to brain: How you know when it's time to go.Current opinion in neurobiology · 2025
    Review
  11. A Spinal Circuit for Modular Gating of Organ Somatosensation.bioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anne M J VerstegenDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Veronique VanderhorstDepartment of Medicine & Neurology, Harvard Medical School, Boston, Massachusetts.
Paul A GrayDepartment of Anatomy & Neurobiology, Washington University School of Medicine, Saint Louis, Missouri.
Mark L ZeidelDepartment of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Joel C GeerlingDepartment of Medicine & Neurology, Harvard Medical School, Boston, Massachusetts.ORCID http://orcid.org/0000-0001-9956-4006
Beth Israel Deaconess Medical Center · USWashington University in St. Louis · US

Funding

TRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5M
CH/BIDMC/Harvard Medical School Neurology Resident Research Education Program Competing RenewalR25NS070682 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI PODURI, ANNAPURNA, SAPER, CLIFFORD B · 2010 to 2023
$4.5M
GENETIC ORGANIZATION OF RESPIRATORY CIRCUITS IN MOUSE BRAINSTEMR01HL089742 · NHLBI · WASHINGTON UNIVERSITY · PI GRAY, PAUL ANDREW · 2009 to 2013
$2.1M
Mapping brainstem control of continenceR01DK113030 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ZEIDEL, MARK L. · 2017 to 2021
$1.9M
Functions and connections of inhibitory reticulospinal locomotor systemsR01NS079623 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI VANDERHORST, VERONIQUE · 2012 to 2016
$1.9M
PB-FI connectivity and arousalK08NS099425 · NINDS · UNIVERSITY OF IOWA · PI GEERLING, JOEL CHARLES · 2017 to 2021
$961k
ProjectP20DK103086 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MATHAI, JOHN · 2014 to 2015
$694k
NHLBI NIH HHS R01 HL089742NHLBI NIH HHS T32 HL007901NIDDK NIH HHS P20 DK103086NIDDK NIH HHS R01 DK113030NINDS NIH HHS K08 NS099425NINDS NIH HHS R01 NS079623NINDS NIH HHS R25 NS070682
6 · The paper itself

Abstract

Barrington's nucleus (Bar) is thought to contain neurons that trigger voiding and thereby function as the "pontine micturition center." Lacking detailed information on this region in mice, we examined gene and protein markers to characterize Bar and the neurons surrounding it. Like rats and cats, mice have an ovoid core of medium-sized Bar neurons located medial to the locus coeruleus (LC). Bar neurons express a GFP reporter for Vglut2, develop from a Math1/Atoh1 lineage, and exhibit immunoreactivity for NeuN. Many neurons in and around this core cluster express a reporter for corticotrophin-releasing hormone (Bar

Indexed as

AnimalsAnimals, NewbornBarrington's NucleusFemaleMaleMiceMice, Inbred C57BLMice, TransgenicNeural PathwaysPonsUrinationbladdercontinencedorsal gray commissure nucleusFoxP2locus coeruleusmath1/atoh1micturitionneuroanatomyneurourologypelvic autonomicpontine central graypontospinalpre-locus coeruleussacral intermediolateral nucleusurethral sphinctervoiding

Identifiers

PMID28340519
PMCPMC5832452
OpenAlexW2601351988

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.