ArticleAlcoholism, clinical and experimental research2017
Academic Difficulties in Children with Prenatal Alcohol Exposure: Presence, Profile, and Neural Correlates.
Article in Alcoholism, clinical and experimental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prenatal alcohol exposure and associations with physical size, dysmorphology and neurodevelopment: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- Prenatal Alcohol Exposure Predicts Academic Outcomes from Childhood to Adolescence: A Prospective Longitudinal Study Based on Meconium Ethyl Glucuronide.Behavioral sciences (Basel, Switzerland) · 2026Article
- Cognitive Processes Influencing Written Sentence Construction in School-Aged Children With Prenatal Alcohol Exposure.Psychology in the schools · 2025Article
- Clustering of circumstances during the first 1000 days after conception and their association with school performance: a population-based cohort study from the Netherlands.BMJ public health · 2025Article
- Perinatal influences on academic achievement and the developing brain: a scoping systematic review.Frontiers in psychology · 2024Article
- Machine learning algorithms to the early diagnosis of fetal alcohol spectrum disorders.Frontiers in neuroscience · 2024Article
- Examining the effects of prenatal alcohol exposure on performance of the sustained attention to response task in children with an FASD.Human brain mapping · 2023Article
- Spiral drawing deficits in children with prenatal alcohol exposure.Alcohol, clinical & experimental research · 2023Article
- Dose-Related Reduction in Hippocampal Neuronal Populations in Fetal Alcohol Exposed Vervet Monkeys.Brain sciences · 2022Article
- Magnitude comparison and automaticity in number processing in adolescents with prenatal alcohol exposure: An event-related potentials study.Alcoholism, clinical and experimental research · 2022Article
- Distinctive neural correlates of phonological and reading impairment in fetal alcohol-exposed adolescents with and without facial dysmorphology.Neuropsychologia · 2022Article
- Characterizing Alcohol-Related Neurodevelopmental Disorder: Prenatal Alcohol Exposure and the Spectrum of Outcomes.Alcoholism, clinical and experimental research · 2020Article
- Prenatal Alcohol Exposure Alters Error Detection During Simple Arithmetic Processing: An Electroencephalography Study.Alcoholism, clinical and experimental research · 2020Article
- Fetal Alcohol Spectrum Disorders: A Review of the Neurobehavioral Deficits Associated With Prenatal Alcohol Exposure.Alcoholism, clinical and experimental research · 2019Review
- Regional Patterns of Alcohol-Induced Neuronal Loss Depend on Genetics: Implications for Fetal Alcohol Spectrum Disorder.Alcoholism, clinical and experimental research · 2018Article
- Neural correlates of verbal memory in youth with heavy prenatal alcohol exposure.Brain imaging and behavior · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAcademic achievement was evaluated in children with heavy prenatal alcohol exposure to determine potential strengths and weaknesses, evaluate the utility of different definitions for identifying low academic performance, and explore the neural correlates that may underlie academic performance.
methodsChildren (8 to 16 years) were assessed using the WIAT-II. Patterns of performance were examined in 2 subject groups: children with heavy prenatal alcohol exposure (n = 67) and controls (n = 61). A repeated-measures MANCOVA examining group differences on academic domain (reading, spelling, math) scores was conducted. Post hoc comparisons examined within-group profiles. Numbers and percentage of children with low achievement were calculated using several criteria. In a subsample (n = 42), neural correlates were analyzed using FreeSurfer v5.3 to examine relations between cortical structure (thickness and surface area) and performance.
resultsThe alcohol-exposed group performed worse than controls on all domains and had a unique academic profile, supported by a significant group × academic domain interaction (p < 0.001). For the alcohol-exposed group, math reasoning was significantly lower than numerical operations, which was significantly lower than spelling and word reading. Over half of the alcohol-exposed group (58.2%) demonstrated low achievement on 1 or more academic domains. The number and percentage of children meeting criteria for low achievement varied based on the domain and definition used. The imaging analysis identified several surface area clusters that were differentially related to math (L superior parietal and R lateral/middle occipital) and spelling (bilateral inferior and medial temporal) performance by group, with no relations for the other academic domains. Generally, scores improved as surface area decreased in controls, whereas no relation or a positive relation was observed in the alcohol-exposed group.
conclusionsAlcohol-exposed children demonstrated deficits in academic performance across domains and definitions, with a relative weakness in math functioning. Atypical brain development may contribute to these impairments in academic achievement. Understanding academic difficulties can assist in advocating effectively for alcohol-exposed children.
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