Evidence map›Paper›PMID 28340489›Full record

ArticleAging2017

MiR-34a-3p alters proliferation and apoptosis of meningioma cells

Tamara V Werner, Martin Hart, Ruth Nickels, Yoo-Jin Kim, Michael D Menger, Rainer M Bohle, Andreas Keller, Nicole Ludwig, Eckart Meese

Open access · greenAbstract read
In one paragraph

Article in Aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. The Epigenetic Landscape of Meningiomas.Advances in experimental medicine and biology · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tamara V WernerInstitute of Human Genetics, Medical School, Saarland University, 66421 Homburg/Saar, Germany.
Martin HartInstitute of Human Genetics, Medical School, Saarland University, 66421 Homburg/Saar, Germany.
Ruth NickelsInstitute for Clinical and Experimental Surgery, Medical School, Saarland University, 66421 Homburg/Saar, Germany.
Yoo-Jin KimInstitute of Pathology, Medical Center, Saarland University, 66421 Homburg/Saar, Germany.
Michael D MengerInstitute for Clinical and Experimental Surgery, Medical School, Saarland University, 66421 Homburg/Saar, Germany.
Rainer M BohleInstitute of Pathology, Medical Center, Saarland University, 66421 Homburg/Saar, Germany.
Andreas KellerClinical Bioinformatics, Saarland University, 66123 Saarbruecken, Germany.
Nicole LudwigInstitute of Human Genetics, Medical School, Saarland University, 66421 Homburg/Saar, Germany.
Eckart MeeseInstitute of Human Genetics, Medical School, Saarland University, 66421 Homburg/Saar, Germany.
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micro (mi)RNAs are short, noncoding RNAs and deregulation of miRNAs and their targets are implicated in tumor generation and progression in many cancers. Meningiomas are mostly benign, slow growing tumors of the central nervous system with a small percentage showing a malignant phenotype.Following

Indexed as

Adaptor Proteins, Signal TransducingApoptosisCell Line, TumorCell ProliferationComputer SimulationGene Expression Regulation, NeoplasticHumansIntracellular Signaling Peptides and ProteinsMeningeal NeoplasmsMeningiomaMicroRNAsProto-Oncogene ProteinsProto-Oncogene Proteins c-bcl-2Signal TransductionSmad4 ProteinAdaptor Proteins, Signal TransducingBCL2 protein, humanFRAT1 protein, humanIntracellular Signaling Peptides and ProteinsMicroRNAsMIRN34 microRNA, humanProto-Oncogene ProteinsProto-Oncogene Proteins c-bcl-2Smad4 ProteinBCL2FRAT1meningiomamiR-34a-3pSMAD4

Identifiers

PMID28340489
PMCPMC5391240
OpenAlexW2599595722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.