SynthesisTransactions of the Royal Society of Tropical Medicine and Hygiene2017
Preventive chemotherapy in one year reduces by over 80% the number of individuals with soil-transmitted helminthiases causing morbidity: results from meta-analysis.
Synthesis in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 34 citations in OpenAlex.
- Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted helminths in three endemic countries.PLoS neglected tropical diseases · 2019Trial
- Coinfection with malaria alters the fecundity and within-host persistence of an intestinal nematode.PLoS neglected tropical diseases · 2026Article
- Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Infectious Diseases.Acta medica Philippina · 2026Article
- Prevalence, Pathology, and Alternative Control of Intestinal Parasites.Pathogens (Basel, Switzerland) · 2025Article
- Coverage and determinants of deworming uptake among under-five children in Somalia: A multilevel analysis of the 2020 SDHS data.PloS one · 2025Article
- The Role of Helminthophagous Fungi in the Biological Control of Human and Zoonotic Intestinal Helminths.Pathogens (Basel, Switzerland) · 2024Review
- Efficacy of Single-Dose Albendazole and Albendazole Plus Ivermectin for Soil-Transmitted Helminth Infection in Children in the Peruvian Amazon.The American journal of tropical medicine and hygiene · 2024Observational
- Human parasitic infections of the class Adenophorea: global epidemiology, pathogenesis, prevention and control.Infectious diseases of poverty · 2024Review
- Optimizing Implementation of Preventive Chemotherapy against Soil-Transmitted Helminthiasis and Intestinal Schistosomiasis Using High-Resolution Data: Field-Based Experiences from Côte d'Ivoire.Diseases (Basel, Switzerland) · 2022Article
- Assessment of environmental contamination with soil-transmitted helminths life stages at school compounds, households and open markets in Jimma Town, Ethiopia.PLoS neglected tropical diseases · 2022Article
- Cross-sectional study on intestinal parasite infections in different ecological zones of the Department of La Paz, Bolivia.One health (Amsterdam, Netherlands) · 2021Article
- Deworming women of reproductive age during adolescence and pregnancy: what is the impact on morbidity from soil-transmitted helminths infection?Parasites & vectors · 2021Article
- The global progress of soil-transmitted helminthiases control in 2020 and World Health Organization targets for 2030.PLoS neglected tropical diseases · 2020Article
- Estimated need for anthelminthic medicines to control soil-transmitted helminthiases in school-aged children, 2020-2030.Infectious diseases of poverty · 2020Article
- Efficacy and safety of ascending dosages of albendazole againstEClinicalMedicine · 2020Article
- Anthelmintic drug discovery: target identification, screening methods and the role of open science.Beilstein journal of organic chemistry · 2020Review
- Sustained preventive chemotherapy for soil-transmitted helminthiases leads to reduction in prevalence and anthelminthic tablets required.Infectious diseases of poverty · 2019Article
- Challenges and opportunities for control and elimination of soil-transmitted helminth infection beyond 2020.PLoS neglected tropical diseases · 2019Article
- The public health benefit and burden of mass drug administration programs in Vietnamese schoolchildren: Impact of mebendazole.PLoS neglected tropical diseases · 2018Article
- Preventive chemotherapy to control soil-transmitted helminthiasis averted more than 500 000 DALYs in 2015.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2017Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The morbidity due to Ascaris lumbricoides and Trichuris trichiura is caused by infections of moderate and heavy intensity while hookworm infections of all intensities are recognized to cause morbidity. This study aims to evaluate the effect of repeated rounds of preventive chemotherapy on the proportion of soil-transmitted helminth (STH) infections causing morbidity. We identified studies from 17 countries, reporting changes in the proportion of STH infection causing morbidity between baseline and follow-up. In the studies identified, the average proportion of individuals with STH infections of moderate and heavy intensity was of 14% at baseline and was on average reduced to 2% by the intervention (i.e., 85% reduction). There was an average reduction of 73% after the first year of treatment, which reached almost 80% after 5 years and over 95% in 10 years of deworming interventions. The reduction in hookworm prevalence was 57% after 12 months reaching 78% after 5 years. We consider the results presented in this study especially useful for decision makers as it demonstrates the effectiveness of preventive chemotherapy in reducing STH prevalence and morbidity. We encourage the implementation of deworming programs to achieve the goal, set by WHO for 2020, to eliminate STH morbidity in children.
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