Evidence map›Paper›PMID 28339791›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2017

BRIDG: a domain information model for translational and clinical protocol-driven research.

Lauren B Becnel, Smita Hastak, Wendy Ver Hoef, Robert P Milius, MaryAnn Slack, Diane Wold, Michael L Glickman, Boris Brodsky, Charles Jaffe, Rebecca Kush and 1 more

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. NCI Imaging Data Commons.Cancer research · 2021
    Article
  6. Challenges in Using a Graph Database to Represent and Analyze Mappings of Cancer Study Data Standards.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020
    Article
  7. Article
  8. Article
  9. Clinical Concept Value Sets and Interoperability in Health Data Analytics.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lauren B BecnelClinical Data Interchange Standards Consortium, Austin, TX, USA.
Smita HastakSamvit Solutions LLC, Reston, VA, USA.
Wendy Ver HoefSamvit Solutions LLC, Reston, VA, USA.
Robert P MiliusNational Marrow Donor Program, Minneapolis, MN, USA.
MaryAnn SlackFood and Drug Administration Office of Strategic Programs, Silver Spring, MD, USA.
Diane WoldClinical Data Interchange Standards Consortium, Austin, TX, USA.
Michael L GlickmanComputer Network Architects Inc. and ISO/TC 215 Health Informatics, Rockville, MD, USA.
Boris BrodskyFood and Drug Administration Office of Strategic Programs, Silver Spring, MD, USA.
Charles JaffeHL7 (Health Level 7 International), Ann Arbor, MI, USA.
Rebecca KushClinical Data Interchange Standards Consortium, Austin, TX, USA.
Edward HeltonNational Cancer Institute, Rockville, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is critical to integrate and analyze data from biological, translational, and clinical studies with data from health systems; however, electronic artifacts are stored in thousands of disparate systems that are often unable to readily exchange data.

objectiveTo facilitate meaningful data exchange, a model that presents a common understanding of biomedical research concepts and their relationships with health care semantics is required. The Biomedical Research Integrated Domain Group (BRIDG) domain information model fulfills this need. Software systems created from BRIDG have shared meaning "baked in," enabling interoperability among disparate systems. For nearly 10 years, the Clinical Data Standards Interchange Consortium, the National Cancer Institute, the US Food and Drug Administration, and Health Level 7 International have been key stakeholders in developing BRIDG.

methodsBRIDG is an open-source Unified Modeling Language-class model developed through use cases and harmonization with other models.

resultsWith its 4+ releases, BRIDG includes clinical and now translational research concepts in its Common, Protocol Representation, Study Conduct, Adverse Events, Regulatory, Statistical Analysis, Experiment, Biospecimen, and Molecular Biology subdomains.

interpretationThe model is a Clinical Data Standards Interchange Consortium, Health Level 7 International, and International Standards Organization standard that has been utilized in national and international standards-based software development projects. It will continue to mature and evolve in the areas of clinical imaging, pathology, ontology, and vocabulary support. BRIDG 4.1.1 and prior releases are freely available at https://bridgmodel.nci.nih.gov .

Indexed as

Biomedical ResearchSemantic WebHealth Information InteroperabilitySoftwareTerminology as Topicclinical trialsdata modelingdata sharingpharmacogeneticstranslational medical research

Identifiers

PMID28339791
PMCPMC6259662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.