ArticleJournal of the American Medical Informatics Association : JAMIA2017
Addressing Beacon re-identification attacks: quantification and mitigation of privacy risks.
Article in Journal of the American Medical Informatics Association : JAMIA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Context of data sharing practices in collaborative human genomic research in low and middle income countries: A systematic review.PloS one · 2026Pooled it
- A systematic literature review of individuals' perspectives on privacy and genetic information in the United States.PloS one · 2018Pooled it
- Enhancing semantic interoperability in precision medicine: converting OMOP CDM to Beacon v2 in the Spanish IMPaCT-Data project.BMC medical informatics and decision making · 2026Article
- The Portuguese Beacon: sharing genomic variant data safely.Database : the journal of biological databases and curation · 2026Article
- CITADEL: a post-quantum secure blockchain framework for privacy-preserving electronic health records with temporally-partitioned federated learning.Frontiers in artificial intelligence · 2026Article
- GENESIS-SHIELD: an interpretable ensemble for anomaly detection in CRISPR genomic-workflow security.Frontiers in artificial intelligence · 2026Article
- Biomedical data repositories require governance for artificial intelligence/machine learning applications at every step.JAMIA open · 2025Article
- A reinforcement learning-based approach for dynamic privacy protection in genomic data sharing beacons.Genome biology · 2025Article
- Toward owner governance in genomic data privacy with Governome.Cell reports methods · 2025Article
- Beacon Reconstruction Attack: Reconstruction of genomes in genomic data-sharing beacons using summary statistics.Bioinformatics (Oxford, England) · 2025Article
- FedGMMAT: Federated generalized linear mixed model association tests.PLoS computational biology · 2024Article
- Assessing Privacy Vulnerabilities in Genetic Data Sets: Scoping Review.JMIR bioinformatics and biotechnology · 2024Article
- Future-proofing genomic data and consent management: a comprehensive review of technology innovations.GigaScience · 2024Review
- The BioRef Infrastructure, a Framework for Real-Time, Federated, Privacy-Preserving, and Personalized Reference Intervals: Design, Development, and Application.Journal of medical Internet research · 2023Article
- COLLAGENE enables privacy-aware federated and collaborative genomic data analysis.Genome biology · 2023Article
- Enabling tradeoffs in privacy and utility in genomic data Beacons and summary statistics.Genome research · 2023Article
- Sociotechnical safeguards for genomic data privacy.Nature reviews. Genetics · 2022Review
- Functional genomics data: privacy risk assessment and technological mitigation.Nature reviews. Genetics · 2022Review
- Computational tools for genomic data de-identification: facilitating data protection law compliance.Nature communications · 2021Article
- Re-identification of individuals in genomic datasets using public face images.Science advances · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 7 institutions in 3 countries.
Funding
Abstract
The Global Alliance for Genomics and Health (GA4GH) created the Beacon Project as a means of testing the willingness of data holders to share genetic data in the simplest technical context-a query for the presence of a specified nucleotide at a given position within a chromosome. Each participating site (or "beacon") is responsible for assuring that genomic data are exposed through the Beacon service only with the permission of the individual to whom the data pertains and in accordance with the GA4GH policy and standards.While recognizing the inference risks associated with large-scale data aggregation, and the fact that some beacons contain sensitive phenotypic associations that increase privacy risk, the GA4GH adjudged the risk of re-identification based on the binary yes/no allele-presence query responses as acceptable. However, recent work demonstrated that, given a beacon with specific characteristics (including relatively small sample size and an adversary who possesses an individual's whole genome sequence), the individual's membership in a beacon can be inferred through repeated queries for variants present in the individual's genome.In this paper, we propose three practical strategies for reducing re-identification risks in beacons. The first two strategies manipulate the beacon such that the presence of rare alleles is obscured; the third strategy budgets the number of accesses per user for each individual genome. Using a beacon containing data from the 1000 Genomes Project, we demonstrate that the proposed strategies can effectively reduce re-identification risk in beacon-like datasets.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.