Evidence map›Paper›PMID 28339115›Full record

ArticleLasers in surgery and medicine2017

Near-IR and CP-OCT imaging of suspected occlusal caries lesions.

Jacob C Simon, Hobin Kang, Michal Staninec, Andrew T Jang, Kenneth H Chan, Cynthia L Darling, Robert C Lee, Daniel Fried

Abstract read
In one paragraph

Article in Lasers in surgery and medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Active Surveillance of Root Caries in Vivo with CP-OCT.Diagnostics (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Article
  8. Current Status and Trends in Research on Caries Diagnosis: A Bibliometric Analysis.International journal of environmental research and public health · 2022
    Article
  9. Article
  10. Thermal Imaging of Root Caries In Vivo.Journal of dental research · 2020
    Article
  11. Article
  12. Occlusal Caries Detection and Diagnosis Using Visual ICDAS Criteria, Laser Fluorescence Measurements, and Near-Infrared Light Transillumination Images.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020
    Article
  13. Article
  14. Article
  15. Selective ablation of dental caries using coaxial CoLasers in surgery and medicine · 2019
    Article
  16. Article
  17. Assessment of cavitation in artificial approximal dental lesions with near-IR imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2017
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacob C SimonUniversity of California, San Francisco, California 94143-0758.
Hobin KangUniversity of California, San Francisco, California 94143-0758.
Michal StaninecUniversity of California, San Francisco, California 94143-0758.
Andrew T JangUniversity of California, San Francisco, California 94143-0758.
Kenneth H ChanUniversity of California, San Francisco, California 94143-0758.
Cynthia L DarlingUniversity of California, San Francisco, California 94143-0758.
Robert C LeeUniversity of California, San Francisco, California 94143-0758.
Daniel FriedUniversity of California, San Francisco, California 94143-0758.

Funding

Early Caries Detection with Near-IR LightR01DE014698 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRIED, DANIEL · 2002 to 2016
$4.0M
Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCTR01DE017869 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRIED, DANIEL · 2006 to 2014
$2.6M
Methods for Assessing Lesion Depth and Severity with Near-IR LightF30DE026052 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SIMON, JACOB CARMODY · 2016 to 2020
$241k
Spectral and Image-guided Laser Ablation for Dental ApplicationsF31DE026350 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAN, KENNETH HENRY · 2017 to 2018
$76k
NIDCR NIH HHS F30 DE026052NIDCR NIH HHS F31 DE026350NIDCR NIH HHS R01 DE014698NIDCR NIH HHS R01 DE017869
6 · The paper itself

Abstract

introductionRadiographic methods have poor sensitivity for occlusal lesions and by the time the lesions are radiolucent they have typically progressed deep into the dentin. New more sensitive imaging methods are needed to detect occlusal lesions. In this study, cross-polarization optical coherence tomography (CP-OCT) and near-IR imaging were used to image questionable occlusal lesions (QOC's) that were not visible on radiographs but had been scheduled for restoration on 30 test subjects.

methodsNear-IR reflectance and transillumination probes incorporating a high definition InGaAs camera and near-IR broadband light sources were used to acquire images of the lesions before restoration. The reflectance probe utilized cross-polarization and operated at wavelengths from 1,500 to 1,700 nm where there is an increase in water absorption for higher contrast. The transillumination probe was operated at 1,300 nm where the transparency of enamel is highest. Tomographic images (6 × 6 × 7 mm

resultsNear-IR reflectance imaging at 1,500-1,700 nm yielded significantly higher contrast (P < 0.05) of the demineralization in the occlusal grooves compared with visible reflectance imaging. Stains in the occlusal grooves greatly reduced the lesion contrast in the visible range yielding negative values. Only half of the 26 lesions analyzed showed the characteristic surface demineralization and increased reflectivity below the dentinal-enamel junction (DEJ) in 3D OCT images indicative of penetration of the lesion into the dentin.

conclusionThis study demonstrates that near-IR imaging methods have great potential for improving the early diagnosis of occlusal lesions. Lasers Surg. Med. 49:215-224, 2017. © 2017 Wiley Periodicals, Inc.

Indexed as

Image Interpretation, Computer-AssistedAdolescentAdultAnalysis of VarianceCohort StudiesDental CariesDental FissuresFemaleHumansMaleMiddle AgedSpectroscopy, Near-InfraredTomography, Optical CoherenceTooth DemineralizationTransilluminationYoung Adultcaries detectioncross-polarization optical coherence tomographynear-IR imagingocclusal caries

Identifiers

PMID28339115
PMCPMC5367963

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.