ArticleSchizophrenia bulletin2017
Thought Disorder in Schizophrenia and Bipolar Disorder Probands, Their Relatives, and Nonpsychiatric Controls.
Article in Schizophrenia bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Diagnostic Utility of Formal Thought Disorder Between Affective and Non-Affective Psychosis: A Machine Learning Approach.The Psychiatric quarterly · 2026Article
- The Neurobiology of Formal Thought Disorder.Current topics in medicinal chemistry · 2024Review
- Predicting new onset thought disorder in early adolescence with optimized deep learning implicates environmental-putamen interactions.medRxiv : the preprint server for health sciences · 2023Article
- Linguistic and non-linguistic markers of disorganization in psychotic illness.Schizophrenia research · 2023Article
- Language abnormalities in schizophrenia: binding core symptoms through contemporary empirical evidence.Schizophrenia (Heidelberg, Germany) · 2022Review
- The shallow cognitive map hypothesis: A hippocampal framework for thought disorder in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2022Review
- Differences in single positive formal thought disorder symptoms between closely matched acute patients with schizophrenia and mania.European archives of psychiatry and clinical neuroscience · 2022Article
- Thought Disorder as a Neglected Dimension in Schizophrenia.Alpha psychiatry · 2022Review
- Assessing the dimensionality of scores derived from the Revised Formal Thought Disorder Self-Report Scale in schizotypy.PloS one · 2022Article
- The cognitive aspect of formal thought disorder and its relationship with global social functioning and the quality of life in schizophrenia.Social psychiatry and psychiatric epidemiology · 2021Article
- Cross Talk: The Microbiota and Neurodevelopmental Disorders.Frontiers in neuroscience · 2017Review
Corrections and comments
- Erratum issuedErratum.2018
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
Thought disorder (TD) has long been associated with schizophrenia (SZ) and is now widely recognized as a symptom of mania and other psychotic disorders as well. Previous studies have suggested that the TD found in the clinically unaffected relatives of SZ, schizoaffective and bipolar probands is qualitatively similar to that found in the probands themselves. Here, we examine which quantitative measures of TD optimize the distinction between patients with diagnoses of SZ and bipolar disorder with psychotic features (BP) from nonpsychiatric controls (NC) and from each other. In addition, we investigate whether these same TD measures also distinguish their respective clinically unaffected relatives (RelSZ, RelBP) from controls as well as from each other. We find that deviant verbalizations are significantly associated with SZ and are co-familial in clinically unaffected RelSZ, but are dissociated from, and are not co-familial for, BP disorder. In contrast, combinatory thinking was nonspecifically associated with psychosis, but did not aggregate in either group of relatives. These results provide further support for the usefulness of TD for identifying potential non-penetrant carriers of SZ-risk genes, in turn enhancing the power of genetic analyses. These findings also suggest that further refinement of the TD phenotype may be needed in order to be suitable for use in genetic studies of bipolar disorder.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.