Evidence map›Paper›PMID 28338393›Full record

ReviewMultiple sclerosis (Houndmills, Basingstoke, England)2017

Contraception for women with multiple sclerosis: Guidance for healthcare providers.

Maria K Houtchens, Lauren B Zapata, Kathryn M Curtis, Maura K Whiteman

Open access · bronzeAbstract readReview
In one paragraph

Review in Multiple sclerosis (Houndmills, Basingstoke, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Impact of sex on multiple sclerosis therapy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  4. Review
  5. Expert opinion on the use of contraception in people with multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Updated Perspectives on the Challenges of Managing Multiple Sclerosis During Pregnancy.Degenerative neurological and neuromuscular disease · 2022
    Review
  10. Article
  11. What Can We Learn from Sex Differences in MS?Journal of personalized medicine · 2021
    Article
  12. Effects of the Menstrual Cycle on Neurological Disorders.Current neurology and neuroscience reports · 2021
    Review
  13. Article
  14. Article
  15. Sex effects across the lifespan in women with multiple sclerosis.Therapeutic advances in neurological disorders · 2020
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Maria K HoutchensDepartment of Neurology, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Lauren B ZapataDivision of Reproductive Health, US Centers for Disease Control and Prevention, Chamblee, GA, USA.
Kathryn M CurtisDivision of Reproductive Health, US Centers for Disease Control and Prevention, Chamblee, GA, USA.
Maura K WhitemanDivision of Reproductive Health, US Centers for Disease Control and Prevention, Chamblee, GA, USA.
Centers for Disease Control and Prevention · USHarvard University · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Family planning is essential for any comprehensive treatment plan for women of reproductive age with multiple sclerosis (MS), including counseling on using effective contraception to optimally time desired and prevent unintended pregnancies. This topical review summarizes the first evidence-based recommendations on contraception safety for women with MS. In 2016, evidence-based recommendations for contraceptive use by women with MS were included in US Medical Eligibility Criteria for Contraceptive Use. They were developed after review of published scientific evidence on contraception safety and consultation with experts. We summarize and expand on the main conclusions of the Centers for Disease Control and Prevention guidance. Most contraceptive methods appear based on current evidence to be safe for women with MS. The only restriction is use of combined hormonal contraceptives among women with MS with prolonged immobility because of concerns about possible venous thromboembolism. Disease-modifying therapies (DMTs) do not appear to decrease the effectiveness of hormonal contraception although formal drug-drug interaction studies are limited. Neurologists can help women with MS make contraceptive choices that factor their level of disability, immobility, and medication use. For women with MS taking potentially teratogenic medications, highly effective methods that are long-acting (e.g. intrauterine devices, implants) might be the best option.

Indexed as

Multiple SclerosisAdultContraceptionContraceptive Agents, FemaleContraceptive Devices, FemaleFemaleHumansPractice Guidelines as TopicContraceptive Agents, Femalecontraceptionevidence-based practiceMultiple sclerosispractice guidelines

Identifiers

PMID28338393
PMCPMC5785786
OpenAlexW2598123523

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.