ArticleScientific reports2017
Halo-free Phase Contrast Microscopy.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Halo-free quantitative phase imaging via physics-constrained self-supervised network.Journal of biomedical optics · 2026Article
- Wavelength and Polarization Multiplexed Nonlocal Metasurface for Quantitative Phase Microscopy.Nanophotonics (Berlin, Germany) · 2026Article
- Automated smartphone based cell analysis platform.Npj imaging · 2025Article
- Quantitative phase microscopies: accuracy comparison.Light, science & applications · 2024Review
- Data-driven classification of individual cells by their non-Markovian motion.Biophysical journal · 2024Article
- Quantitative phase imaging by gradient retardance optical microscopy.Scientific reports · 2024Article
- Adaptive constraints by morphological operations for single-shot digital holography.Scientific reports · 2023Article
- Quantitative phase contrast imaging with a nonlocal angle-selective metasurface.Nature communications · 2022Article
- Density fluctuations, homeostasis, and reproduction effects in bacteria.Communications biology · 2022Article
- Self-calibrated 3D differential phase contrast microscopy with optimized illumination.Biomedical optics express · 2022Article
- Wide-Field Mid-Infrared Hyperspectral Imaging by Snapshot Phase Contrast Measurement of Optothermal Excitation.Analytical chemistry · 2021Article
- Spatial light interference microscopy: principle and applications to biomedicine.Advances in optics and photonics · 2021Article
- Article
- Minimizing scattering-induced phase errors in differential interference contrast microscopy.Journal of biomedical optics · 2020Article
- High-speed interferometric imaging reveals dynamics of neuronal deformation during the action potential.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Epi-illumination gradient light interference microscopy for imaging opaque structures.Nature communications · 2019Article
- Epi-mode tomographic quantitative phase imaging in thick scattering samples.Biomedical optics express · 2019Article
- Video-rate quantitative phase analysis by a DIC microscope using a polarization camera.Biomedical optics express · 2019Article
- Label-free classification of cells based on supervised machine learning of subcellular structures.PloS one · 2019Article
- Quantitative assessment of cancer cell morphology and motility using telecentric digital holographic microscopy and machine learning.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
We present a new approach for retrieving halo-free phase contrast microscopy (hfPC) images by upgrading the conventional PC microscope with an external interferometric module, which generates sufficient data for reversing the halo artifact. Acquiring four independent intensity images, our approach first measures haloed phase maps of the sample. We solve for the halo-free sample transmission function by using a physical model of the image formation under partial spatial coherence. Using this halo-free sample transmission, we can numerically generate artifact-free PC images. Furthermore, this transmission can be further used to obtain quantitative information about the sample, e.g., the thickness with known refractive indices, dry mass of live cells during their cycles. We tested our hfPC method on various control samples, e.g., beads, pillars and validated its potential for biological investigation by imaging live HeLa cells, red blood cells, and neurons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.