Evidence map›Paper›PMID 28337995›Full record

ArticleScientific reports2017

Cigarette Smoke Impairs A

Zhi Tian, Hui Zhang, Jendayi Dixon, Nicole Traphagen, Todd A Wyatt, Kusum Kharbanda, Samantha Simet Chadwick, Narasaiah Kolliputi, Diane S Allen-Gipson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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  8. DUOX1 in mammalian disease pathophysiology.Journal of molecular medicine (Berlin, Germany) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zhi TianDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa FL, USA.
Hui ZhangDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
Jendayi DixonDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa FL, USA.
Nicole TraphagenDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa FL, USA.
Todd A WyattDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
Kusum KharbandaResearch Service, Omaha-Western Iowa Veterans Affairs Medical Center, Omaha, NE, USA.
Samantha Simet ChadwickDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
Narasaiah KolliputiDivision of Allergy and Immunology, Department of Internal Medicine, College of Medicine, University of South Florida, Tampa FL, USA.
Diane S Allen-GipsonDepartment of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa FL, USA.
University of South Florida · USUniversity of Nebraska Medical Center · USNebraska Medical Center · USOmaha VA Medical Center · US

Funding

Molecular Mechanisms of Hyperoxic Lung InjuryR01HL105932 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI KOLLIPUTI, NARASAIAH · 2011 to 2019
$2.9M
Airway Injury Caused by MAA AdductsR01AA017993 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WYATT, TODD A · 2008 to 2012
$1.9M
Adenosine regulation of airway wound repairK01HL084684 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI ALLEN-GIPSON, DIANE S · 2006 to 2010
$678k
BLR&D Research Career Scientist AwardIK6BX003781 · VA · OMAHA VA MEDICAL CENTER · PI WYATT, TODD A · 2017 to 2021
–
BLRD VA I01 BX000728BLRD VA IK6 BX003781NHLBI NIH HHS K01 HL084684NHLBI NIH HHS R01 HL105932NIAAA NIH HHS R01 AA017993
6 · The paper itself

Abstract

Cigarette smoke (CS) exposure and intrinsic factors such as the NADPH oxidases produce high levels of reactive oxygen species (ROS), ensuing inflammatory tissue injury. We previously demonstrated that CS-generated ROS, particularly hydrogen peroxide (H

Indexed as

AnimalsBronchiCalcium IonophoresCell LineComplex MixturesDual OxidasesEnzyme InhibitorsEpithelial CellsGene Expression RegulationHumansHydrogen PeroxideMiceMice, Inbred C57BLNicotianaOnium CompoundsProtein Kinase C-alphaCalcium IonophoresComplex MixturesdiphenyleneiodoniumDual OxidasesDuox1 protein, mouseEnzyme InhibitorsHydrogen PeroxideOnium CompoundsProtein Kinase C-alphaReceptor, Adenosine A2AThapsigargin

Identifiers

PMID28337995
PMCPMC5364501
OpenAlexW2598745295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.