ArticleFEBS letters2017
Modulation of Escherichia coli serine acetyltransferase catalytic activity in the cysteine synthase complex.
Article in FEBS letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- The Evolutionary Maintenance of Amino Acid Prototrophy in Escherichia coli.Genome biology and evolution · 2026Article
- Serine Acetyltransferase fromInternational journal of molecular sciences · 2026Article
- The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria.Proteins · 2026Article
- Article
- Context-dependent serotonin signaling links dietary quality to foraging decisions.Nature communications · 2025Article
- Benzotriazole derivatives as alternateiScience · 2025Article
- Analysis of stress response in multiple bacterial pathogens using a network biology approach.Scientific reports · 2025Article
- Identification of novel inhibitors targeting serine acetyltransferase from Neisseria gonorrhoeae.Computational and structural biotechnology journal · 2025Article
- Priestia aryabhattai MBM3-Mediated Enhancement of Sulphur Metabolism in Brassica campestris.Current microbiology · 2024Article
- CysB Is a Key Regulator of the Antifungal Activity ofInternational journal of molecular sciences · 2023Article
- Combatting antimicrobial resistance via the cysteine biosynthesis pathway in bacterial pathogens.Bioscience reports · 2022Review
- Serine acetyltransferase from Neisseria gonorrhoeae; structural and biochemical basis of inhibition.The Biochemical journal · 2022Article
- The Nervous System Contributes to the Tumorigenesis and Progression of Human Digestive Tract Cancer.Journal of immunology research · 2022Review
- Enhancement of Campylobacter hepaticus culturing to facilitate downstream applications.Scientific reports · 2021Article
- Refining the structure-activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms.Journal of enzyme inhibition and medicinal chemistry · 2019Article
- Combination of SAXS and Protein Painting Discloses the Three-Dimensional Organization of the Bacterial Cysteine Synthase Complex, a Potential Target for Enhancers of Antibiotic Action.International journal of molecular sciences · 2019Article
- Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase.Scientific reports · 2017Article
- Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
Abstract
In bacteria and plants, serine acetyltransferase (CysE) and O-acetylserine sulfhydrylase-A sulfhydrylase (CysK) collaborate to synthesize l-Cys from l-Ser. CysE and CysK bind one another with high affinity to form the cysteine synthase complex (CSC). We demonstrate that bacterial CysE is activated when bound to CysK. CysE activation results from the release of substrate inhibition, with the K
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.