ArticleEJNMMI research2017
Comparison of diagnostic performance of four software packages for phase dyssynchrony analysis in gated myocardial perfusion SPECT.
Article in EJNMMI research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of left ventricular mechanical dyssynchrony indices derived from gated myocardial perfusion SPECT in coronary artery disease: a systematic review and meta-analysis.Annals of nuclear medicine · 2024Pooled it
- Phase entropy of gated SPECT-MPI for predicting major adverse cardiovascular events: incremental prognostic value beyond perfusion and function.Frontiers in cardiovascular medicine · 2026Article
- A New Method Using Deep Learning to Predict the Response to Cardiac Resynchronization Therapy.Journal of imaging informatics in medicine · 2025Article
- Incremental prognostic value of stress phase entropy over standard PET myocardial perfusion imaging variables.European journal of nuclear medicine and molecular imaging · 2023Article
- The Value of Stress-Gated Blood Pool SPECT in Predicting Early Postoperative Period Complications in Ischemic Cardiomyopathy Patients: Focus on Mechanical Dyssynchrony.Journal of clinical medicine · 2023Article
- Myocardial scar reduction after cardiac resynchronization therapy assessed by gated myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Comparing left ventricular mechanical dyssynchrony between diabetic and non-diabetic patients with normal gated SPECT MPI.The international journal of cardiovascular imaging · 2022Article
- Mechanical dyssynchrony & CRT: Is it time for guideline updates?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- The rate of myocardial perfusion recovery after steroid therapy and its implication for cardiac events in cardiac sarcoidosis and primarily preserved left ventricular ejection fraction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Prognostic Value of Phase Analysis for Predicting Adverse Cardiac Events Beyond Conventional Single-Photon Emission Computed Tomography Variables: Results From the REFINE SPECT Registry.Circulation. Cardiovascular imaging · 2021Observational
- Phase analysis of gated myocardial perfusion SPECT and cardiac resynchronization therapy: The good, the bad, and the ugly.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Demystifying dyssynchrony for diagnosis and prognosis: Tips for measuring heterogeneous phase distribution.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- What does entropy reveal in phase analysis of myocardial perfusion SPECT?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Useful assessment of myocardial viability and dyssynchrony from gated perfusion scintigraphy for better qualification for resynchronization therapy. Part 3.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2020Review
- Phase dyssynchrony andJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Making the invisible visible: Phase dyssynchrony has potential as a new prognostic marker.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Is it time for personalized cardiac resynchronization therapy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Comparison of Left Ventricular Phase Parameters Analysis between Two Software Programs in Patients with Normal Gated Single-photon Emission Computed Tomography-Myocardial Perfusion Imaging.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
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9 authors.
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Abstract
backgroundPhase analysis of gated myocardial perfusion single-photon emission computed tomography (SPECT) for assessment of left ventricular (LV) dyssynchrony was investigated using the following dedicated software packages: Corridor4DM (4DM), cardioREPO (cREPO), Emory Cardiac Toolbox (ECTb), and quantitative gated SPECT (QGS). The purpose of this study was to evaluate the normal values of 95% histogram bandwidth, phase standard deviation (SD), and entropy and to compare the diagnostic performance of the four software packages. A total of 122 patients with normal myocardial perfusion and cardiac function (58.9 ± 12.3 years, 60 women, ejection fraction (EF) 74.3 ± 5.7%, and end-diastolic volume (EDV) 83.5 ± 3.6 mL) and 34 patients with suspected LV dyssynchrony (64.1 ± 12.2 years, 9 women, EF 52.0 ± 18.0%, and EDV 145.0 ± 6.8 mL) who underwent Tc-99m methoxy-isobutyl-isonitrile/tetrofosmin gated SPECT were retrospectively evaluated. Dyssynchrony indices of the 95% histogram bandwidth, phase SD, and entropy were computed with the four software programs. Diagnostic performance of LV phase dyssynchrony assessments was determined by receiver operator characteristic (ROC) analysis. The area under the ROC curve (AUC) was used to compare the software programs. The optimal cutoff point was determined by ROC curve based on the Youden index.
resultsThe average of normal bandwidth significantly differed among the four software programs except in the comparison of 4DM and ECTb. Moreover, the normal phase SD significantly differed among the four software programs except in the comparison of cREPO and ECTb. The software programs showed high correlation levels for bandwidth, phase SD, and entropy (r ≥ 0.73, p < 0.001). ROC AUCs of bandwidth, phase SD, and entropy were ≥0.850, ≥0.858, and ≥0.900, respectively. Moreover, the ROC AUCs of bandwidth, phase SD, and entropy did not significantly differ among the four software programs. Optimal cutoff points for phase parameters were 24°-42° for bandwidth, 8.6°-15.3° for phase SD, and 31-48% for entropy.
conclusionsAlthough the optimal cutoff value for determining LV phase dyssynchrony by ROC analysis varied depending on the use of the different software programs, all software programs can be used reliably for phase dyssynchrony analysis.
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