Evidence map›Paper›PMID 28337598›Full record

ArticleInternational journal of legal medicine2017

Likelihood ratio formulae for disputed parentage when the product of conception is trisomic.

Duncan A Taylor, Oliva Handt, Damien Abarno, John Buckleton

Abstract read
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In one paragraph

Article in International journal of legal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Duncan A TaylorForensic Science South Australia, 21 Divett Place, Adelaide, SA, 5000, Australia. Duncan.Taylor@sa.gov.au.
Oliva HandtForensic Science South Australia, 21 Divett Place, Adelaide, SA, 5000, Australia.
Damien AbarnoForensic Science South Australia, 21 Divett Place, Adelaide, SA, 5000, Australia.
John BuckletonESR, Private Bag 92021, Auckland, 1142, New Zealand.

Funding

US National Institute of Justice 2014-DN-BX-K028
6 · The paper itself

Abstract

We present here the derivation of paternity index formulae that covers situations of a disputed paternity trio with a trisomic product of conception. We consider six possible mechanisms for trisomy to occur: dispermy, dieggy, paternal meiosis I or II, and maternal meiosis I or II in the calculation. We also provide a biological explanation for how each of the mechanisms could give rise to a trisomy. The paper is set out in a general manner so that the tables presented can be used on any instance of trisomic offspring. This work is motivated by a case of disputed paternity where the product of conception was trisomic, i.e. the electropherogram of the product of conception possessed three alleles at each locus. The outcome was extremely strong support for the alleged father's paternity of the product of conception.

Indexed as

Likelihood FunctionsPaternityTrisomyForensic GeneticsGenotypeHumansMaleMeiosisProbabilityTriploidyFormulae look-up tableLikelihood ratioPaternity indexTriploidyTrisomic

Identifiers

PMID28337598

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.