ArticleInternational journal of colorectal disease2017
Comorbidity and the risk of anastomotic leak in Chinese patients with colorectal cancer undergoing colorectal surgery.
Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Preoperative risk factors associated with anastomotic leakage after colectomy for colorectal cancer: a systematic review and meta-analysis.Revista do Colegio Brasileiro de Cirurgioes · 2022Pooled it
- Obesity and anastomotic leak rates in colorectal cancer: a meta-analysis.International journal of colorectal disease · 2021Pooled it
- Truly Inevitable-Our Perspective on the Complications After Surgery for Rectal Cancer.Indian journal of surgical oncology · 2025Article
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- Predictors of outcome for treatment of enterovaginal fistula : Therapeutical strategies for treatment.International journal of colorectal disease · 2023Article
- Feasibility and advantages analyses of wedge resection without mesentery detached approach applied to closure of loop ileostomy.BMC surgery · 2022Article
- Article
- Updates of Risk Factors for Anastomotic Leakage after Colorectal Surgery.Diagnostics (Basel, Switzerland) · 2021Review
- Short and long-term outcomes of elderly patients undergoing left-sided colorectal resection with primary anastomosis for cancer.BMC geriatrics · 2021Article
- Identification of long non-coding RNA SCARNA9L as a novel molecular target for colorectal cancer.Oncology letters · 2020Article
- Surgical complications in colorectal cancer patients.Annals of medicine and surgery (2012) · 2020Review
- Colorectal cancer surgery in selected nonagenarians is relatively safe and it is associated with a good long-term survival: an observational study.World journal of surgical oncology · 2020Observational
- Preoperative C-reactive protein-to-albumin ratio predicts anastomotic leak in elderly patients after curative colorectal surgery.Cancer biomarkers : section A of Disease markers · 2020Article
- Intra-corporeal delta-shaped anastomosis in laparoscopic right hemicolectomy for right colon cancer: a safe and effective technique.Gastroenterology report · 2019Article
- CHAScientific reports · 2017Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeComorbidities had considerable effects on the prognosis in patients with colorectal cancer (CRC). The primary aim of the present study was to examine the influence of comorbidity on the risk of anastomotic leak (AL) in patients with CRC who underwent surgical resection.
methodsUsing the electronic Hospitalization Summary Reports in the top-ranked public hospitals in China, we identified 11,397 patients with CRC undergoing resection surgery from 2013 through 2015. We estimated the risk of AL according to Charlson Comorbidity Index (CCI) score using logistic regression analysis, adjusting for age, sex, and geographic regions.
resultsThe incidence rate of AL in the study population was 1.8% (204/11,397). Multivariable analyses identified male sex and CCI score as independent risk factors for AL. The CCI score had a positive graded association with the risk of AL (P for trend = 0.006). The risk increased by an estimated 10.2% (odds ratio [OR], 1.10; 95% confidence interval [CI], 1.03-1.18) for each additional 1 point in the CCI score. After adjusting for potential confounders, patients with a CCI score ≥3 had 1.82 times (95% CI, 1.24-2.69) higher risk of AL compared with patients with a CCI score of 0.
conclusionThe findings suggested that CCI score was an independent risk factor for the development of AL in Chinese patients with CRC who underwent surgical resection.
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