Evidence map›Paper›PMID 28337570›Full record

ReviewCurrent allergy and asthma reports2017

Economics of Chronic Rhinosinusitis.

Luke Rudmik

4 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 114 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05400616 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Phase-II Randomized Control Trial of Nasal Microbiota Transplant Therapy in Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

TypeinterventionalSponsorThe University of QueenslandRan2022 to 2025Enrolled60ConditionsChronic Rhinosinusitis (Diagnosis)ArmsMicrobiome Transplant, Placebo
NCT06017427 terminatednot on this mapstarted 2023, after this paper: background citation

Evaluation of Patient Satisfaction During Treatment With Dupilumab in Severe and Recurrent Nasosinusal Polyposis Despite Appropriate Medical and Surgical Treatment.

TypeobservationalSponsorIHU StrasbourgRan2023 to 2023Enrolled32ConditionsChronic Rhinosinusitis With Nasal PolypsArmsQuestionnaires
NCT06217419 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Proof of Concept of Remote Management of Chronic Inflammatory Airway Diseases for Patient Empowerment

TypeinterventionalSponsorAzienda Ospedaliero Universitaria di SassariRan2024 to 2026Enrolled136ConditionsChronic Rhinosinusitis With Nasal Polyps, AsthmaArmsRadio Frequency IDentification (RFID) device
NCT07270302 phase1 / phase2not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Safety and Efficacy of Nebulized Nasal Steroids for the Treatment of Chronic Rhinosinusitis

TypeinterventionalSponsorWashington University School of MedicineRan2025 to 2026Enrolled50ConditionsChronic RhinosinusitisArmsnebulized budesonide via NasoNeb, budesonide lavage via NeilMed
3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Efficacy of endoscopic sinus surgery for chronic rhinosinusitis: a systematic review of systematic reviews.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Luke RudmikDivision of Otolaryngology-Head and Neck Surgery, Department of Surgery, Richmond Road Diagnostic and Treatment Centre, University of Calgary, 1820 Richmond Road SW, Calgary, AB, T2T 5C7, Canada. Lukerudmik@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe objective of this article is to provide an updated review of the economic burden of chronic rhinosinusitis (CRS) and discuss how both medical and surgical interventions impact direct and indirect costs related to CRS. By understanding the economics of CRS, clinicians may improve the patient-centeredness of their care and help distinguish between low and high value interventions. RECENT

findingsDirect costs related to CRS are primarily driven by outpatient physician visits, prescription medical therapy, and endoscopic sinus surgery (ESS). CRS produces large indirect costs and these costs often vary based on the severity of the patients CRS-specific QoL impairment. The overall direct cost related to CRS is estimated to range between $10 and $13 billion per year in the USA. The overall indirect cost related to CRS-related losses in work productivity is estimated to be in excess of $20 billion per year. In the appropriate patients with refractory CRS, ESS provides significant reductions in both direct and indirect costs; however, continued medical therapy alone may be a high value intervention in select patients who have lower severity in their baseline QoL and work productivity.

Indexed as

Cost of IllnessHealth Care CostsChronic DiseaseHumansPatient-Centered CareRhinitisSinusitisUnited StatesBurden of diseaseChronic sinusitisCostEconomicPharmacoeconomicsRhinosinusitisValue of care

Identifiers

PMID28337570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.