Evidence map›Paper›PMID 28337464›Full record

ArticleAmerican journal of clinical and experimental urology2017

Obesity, age, ethnicity, and clinical features of prostate cancer patients.

Victor J Wu, Darren Pang, Wendell W Tang, Xin Zhang, Li Li, Zongbing You

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of clinical and experimental urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Victor J WuDepartment of Structural & Cellular Biology, Tulane UniversityNew Orleans, LA, USA; Department of Orthopaedic Surgery, Tulane UniversityNew Orleans, LA, USA.
Darren PangLaboratory of Translational Cancer Research, Ochsner Clinic Foundation New Orleans, LA, USA.
Wendell W TangDepartment of Pathology, Ochsner Clinic Foundation New Orleans, LA, USA.
Xin ZhangLaboratory of Translational Cancer Research, Ochsner Clinic Foundation New Orleans, LA, USA.
Li LiLaboratory of Translational Cancer Research, Ochsner Clinic Foundation New Orleans, LA, USA.
Zongbing YouDepartment of Structural & Cellular Biology, Tulane UniversityNew Orleans, LA, USA; Department of Orthopaedic Surgery, Tulane UniversityNew Orleans, LA, USA; Tulane Cancer Center and Louisiana Cancer Research Consortium, Tulane UniversityNew Orleans, LA, USA; Tulane Center for Stem Cell Research and Regenerative Medicine, Tulane UniversityNew Orleans, LA, USA; Tulane Center for Aging, Tulane UniversityNew Orleans, LA, USA.
Ochsner Medical Center · USTulane University · US

Funding

UNCOVERING THE MECHANISMS OF OSTEOSARCOMA METASTASIS SUPPRESSION BY MTBPP20RR020152 · NCRR · TULANE UNIVERSITY OF LOUISIANA · PI FORTGANG, ILANA · 2004 to 2011
$17.0M
Mentoring a Cancer Genetics ProgramP20GM103518 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI DEININGER, PRESCOTT L. · 2012 to 2013
$4.3M
The role of IL-17 in prostate cancerR01CA174714 · NCI · TULANE UNIVERSITY OF LOUISIANA · PI YOU, ZONGBING · 2013 to 2017
$1.6M
NCI NIH HHS R01 CA174714NCRR NIH HHS P20 RR020152NIGMS NIH HHS P20 GM103518
6 · The paper itself

Abstract

Approximately 36.5% of the U.S. adults (≥ 20 years old) are obese. Obesity has been associated with type 2 diabetes mellitus, cardiovascular disease, stroke, and several types of cancer. The present study included 1788 prostate cancer patients who were treated with radical prostatectomy at the Ochsner Health System, New Orleans, Louisiana, from January, 2001 to March, 2016. The patient's medical records were retrospectively reviewed. Body mass index (BMI), age, ethnicity (Caucasians versus African Americans), clinical stage, Gleason score, and prostate-specific antigen (PSA) levels were retrieved. The relative risk of the patients was stratified into low risk and high risk groups. Associative analyses found that BMI was associated with age, clinical stage, Gleason score, but not ethnicity, PSA levels, or the relative risk in this cohort. Age was associated with ethnicity, clinical stage, Gleason score, and PSA levels, as well as the relative risk. Ethnicity was associated with Gleason score and PSA levels as well as the relative risk, but not clinical stage. These findings suggest that obesity is associated with advanced prostate cancer with stage T3 or Gleason score ≥ 7 diseases, and age and ethnicity are important factors that are associated with the clinical features of prostate cancer patients.

Indexed as

ageclinical stageethnicityGleason scoreobesityProstate cancerPSA

Identifiers

PMID28337464
PMCPMC5344988
OpenAlexW2625475427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.