Evidence map›Paper›PMID 28337438›Full record

ArticleFrontiers in medicine2017

MAGE-A Antigens and Cancer Immunotherapy.

Paul Zajac, Elke Schultz-Thater, Luigi Tornillo, Charlotte Sadowski, Emanuele Trella, Chantal Mengus, Giandomenica Iezzi, Giulio C Spagnoli

Abstract read
In one paragraph

Article in Frontiers in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

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  10. Exploring TCR-like CAR-Engineered Lymphocyte Cytotoxicity against MAGE-A4.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paul ZajacOncology Surgery, Department of Biomedicine, University Hospital of Basel , Basel , Switzerland.
Elke Schultz-ThaterOncology Surgery, Department of Biomedicine, University Hospital of Basel , Basel , Switzerland.
Luigi TornilloDepartment of Pathology, University Hospital of Basel , Basel , Switzerland.
Charlotte SadowskiOncology Surgery, Department of Biomedicine, University Hospital of Basel , Basel , Switzerland.
Emanuele TrellaOncology Surgery, Department of Biomedicine, University Hospital of Basel , Basel , Switzerland.
Chantal MengusOncology Surgery, Department of Biomedicine, University Hospital of Basel , Basel , Switzerland.
Giandomenica IezziCancer Immunotherapy, Department of Biomedicine, University Hospital of Basel , Basel , Switzerland.
Giulio C SpagnoliOncology Surgery, Department of Biomedicine, University Hospital of Basel , Basel , Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MAGE-A antigens are expressed in a variety of cancers of diverse histological origin and germinal cells. Due to their relatively high tumor specificity, they represent attractive targets for active specific and adoptive cancer immunotherapies. Here, we (i) review past and ongoing clinical studies targeting these antigens, (ii) analyze advantages and disadvantages of different therapeutic approaches, and (iii) discuss possible improvements in MAGE-A-specific immunotherapies.

Indexed as

adoptive immunotherapycancer immunotherapycancer–testis antigensclinical trialsMAGE-A

Identifiers

PMID28337438
PMCPMC5340762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.