Evidence map›Paper›PMID 28337428›Full record

ArticleFrontiers in cellular and infection microbiology2017

Niacin-mediated Gene Expression and Role of NiaR as a Transcriptional Repressor of

Muhammad Afzal, Oscar P Kuipers, Sulman Shafeeq

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Characterization of the Nicotinamide Adenine Dinucleotide Biosynthesis Pathway and Regulatory Mechanisms in Streptococcus mutans.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. The activation of the metal-containing regulatory protein NiaR from Thermotoga maritima by its effector, nicotinic acid.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Nicotinamide and Demographic and Disease transitions: Moderation is Best.International journal of tryptophan research : IJTR · 2019
    Review
  12. NADH-Mediated Gene Expression inFrontiers in microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Muhammad AfzalDepartment of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of GroningenGroningen, Netherlands; Department of Bioinformatics and Biotechnology, Government College UniversityFaisalabad, Pakistan.
Oscar P KuipersDepartment of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen Groningen, Netherlands.
Sulman ShafeeqDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet Stockholm, Sweden.
Government College University, Faisalabad · PKKarolinska Institutet · SEUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NAD (Nicotinamide Adenine Dinucleotide) biosynthesis is vital for bacterial physiology and plays an important role in cellular metabolism. A naturally occurring vitamin B complex, niacin (nicotinic acid), is a precursor of coenzymes NAD and NADP. Here, we study the impact of niacin on global gene expression of

Indexed as

Bacterial Proteinsbeta-GalactosidaseGene DeletionGene Expression ProfilingGene Expression Regulation, BacterialGenes, ReporterMicroarray AnalysisNiacinRepressor ProteinsStreptococcus pneumoniaeBacterial Proteinsbeta-GalactosidaseNiacinRepressor ProteinsnadCniacinNiaRniaXPneumococcuspnuC

Identifiers

PMID28337428
PMCPMC5343564
OpenAlexW2593524074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.