Evidence map›Paper›PMID 28337287›Full record

ArticleAmerican journal of translational research2017

MEMRI is a biomarker defining nicotine-specific neuronal responses in subregions of the rodent brain.

Aditya N Bade, Howard E Gendelman, Michael D Boska, Yutong Liu

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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  9. Administration ofFrontiers in behavioral neuroscience · 2020
    Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aditya N BadeDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center Omaha 68198-5880, NE, United States.
Howard E GendelmanDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center Omaha 68198-5880, NE, United States.
Michael D BoskaDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical CenterOmaha 68198-5880, NE, United States; Department of Radiology, University of Nebraska Medical CenterOmaha 68198-5880, NE, United States.
Yutong LiuDepartment of Pharmacology and Experimental Neuroscience, University of Nebraska Medical CenterOmaha 68198-5880, NE, United States; Department of Radiology, University of Nebraska Medical CenterOmaha 68198-5880, NE, United States.
Nebraska Medical Center · USUniversity of Nebraska Medical Center · US

Funding

Pharmacokinetics and Drug-Drug InteractionsP01DA028555 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BOSKA, MICHAEL DOUGLAS · 2010 to 2019
$16.8M
Nebraska Center for VirologyP30GM103509 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2012 to 2014
$3.3M
NIDA NIH HHS P01 DA028555NIGMS NIH HHS P30 GM103509
6 · The paper itself

Abstract

Nicotine dependence is defined by dopaminergic neuronal activation within the nucleus accumbens (ACB) and by affected neural projections from nicotine-stimulated neurons. Control of any subsequent neural activities would underpin any smoking cessation strategy. While extensive efforts have been made to study the pathophysiology of nicotine addiction, more limited works were developed to find imaging biomarkers. If such biomarkers are made available, addictive behaviors could be monitored noninvasively. To such ends, we employed manganese (Mn

Indexed as

addictionManganese-enhanced MRIneuronal activitynicotinesmoking

Identifiers

PMID28337287
PMCPMC5340694
OpenAlexW2613152254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.