Evidence map›Paper›PMID 28337285›Full record

ArticleAmerican journal of translational research2017

Preclinical and clinical evaluation of the liver tumor irreversible electroporation by magnetic resonance imaging.

Matteo Figini, Xifu Wang, Tianchu Lyu, Zhanliang Su, Daniele Procissi, Vahid Yaghmai, Andrew C Larson, Zhuoli Zhang

Abstract read
In one paragraph

Article in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matteo FiginiDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Xifu WangDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Tianchu LyuDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Zhanliang SuDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Daniele ProcissiDepartment of Radiology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
Vahid YaghmaiDepartment of Radiology, Feinberg School of Medicine, Northwestern UniversityChicago, IL, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern UniversityChicago, IL 60611, USA.
Andrew C LarsonDepartment of Radiology, Feinberg School of Medicine, Northwestern UniversityChicago, IL, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern UniversityChicago, IL 60611, USA.
Zhuoli ZhangDepartment of Radiology, Feinberg School of Medicine, Northwestern UniversityChicago, IL, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern UniversityChicago, IL 60611, USA.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
MRI-Guided Dendritic-Cell-Based Vaccine Immunotherapy for Pancreatic CancerR01CA209886 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vahid Yaghmai, Zhuoli Zhang · 2016 to 2026
$3.3M
MRI-Guided Irreversible Electroporation Ablation for Liver TumorsR01CA196967 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZHANG, ZHUOLI · 2015 to 2018
$1.4M
NCI NIH HHS P30 CA060553NCI NIH HHS R01 CA196967NCI NIH HHS R01 CA209886
6 · The paper itself

Abstract

Irreversible electroporation (IRE) is a relatively new technique for tumor ablation. It has shown promising results in difficult cases where surgery is not recommended and delicate anatomic structures are present near or within the tumor. Currently, liver cancer is one of the most common targets for IRE treatment. Pre-operative and post-operative imaging has a key role in IRE procedures and research studies. Although ultrasound is usually the first choice, especially for intra-operative guidance, magnetic resonance imaging (MRI) plays an important role in the visualization and characterization of tumor before and after IRE in clinical and preclinical studies. However, the appearance of liver lesions after IRE with different MRI sequences has never been systematically investigated, and the most common practice is to limit the acquisition protocol to only contrast-enhanced T1-weighted images. In this work, the role of MRI in clinical and preclinical assessment of hepatic tumors treated with IRE is reviewed and discussed.

Indexed as

Irreversible electroporationlivermagnetic resonance imagingtherapy response

Identifiers

PMID28337285
PMCPMC5340692

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.