Evidence map›Paper›PMID 28337251›Full record

ArticleOxidative medicine and cellular longevity2017

Pentaerythritol Tetranitrate In Vivo Treatment Improves Oxidative Stress and Vascular Dysfunction by Suppression of Endothelin-1 Signaling in Monocrotaline-Induced Pulmonary Hypertension.

Sebastian Steven, Matthias Oelze, Moritz Brandt, Elisabeth Ullmann, Swenja Kröller-Schön, Tjebo Heeren, Lan P Tran, Steffen Daub, Mobin Dib, Dirk Stalleicken and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Sebastian StevenCenter for Cardiology, Department of Cardiology, Mainz, Germany; Center of Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
Matthias OelzeCenter for Cardiology, Department of Cardiology, Mainz, Germany.
Moritz BrandtCenter for Cardiology, Department of Cardiology, Mainz, Germany; Center of Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
Elisabeth UllmannCenter for Cardiology, Department of Cardiology, Mainz, Germany.
Swenja Kröller-SchönCenter for Cardiology, Department of Cardiology, Mainz, Germany.
Tjebo HeerenCenter for Cardiology, Department of Cardiology, Mainz, Germany.
Lan P TranCenter for Cardiology, Department of Cardiology, Mainz, Germany.
Steffen DaubCenter for Cardiology, Department of Cardiology, Mainz, Germany.
Mobin DibCenter for Cardiology, Department of Cardiology, Mainz, Germany.
Dirk StalleickenFreelancer Consultant, 76199 Karlsruhe, Germany.
Philip WenzelCenter for Cardiology, Department of Cardiology, Mainz, Germany; Center of Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
Thomas MünzelCenter for Cardiology, Department of Cardiology, Mainz, Germany.
Andreas DaiberCenter for Cardiology, Department of Cardiology, Mainz, Germany.ORCID 0000-0002-2769-0094
Johannes Gutenberg University Mainz · DEFreelancer (Portugal) · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetylcholineAnimalsBlood PressureBody WeightCell LineEchocardiographyEndothelin-1Endothelium, VascularHeartHeme Oxygenase-1HumansHypertension, PulmonaryIntercellular Adhesion Molecule-1MaleMonocrotalineOxidative StressAcetylcholineEndothelin-1Heme Oxygenase-1Intercellular Adhesion Molecule-1MonocrotalinePentaerythritol TetranitrateVasodilator Agents

Identifiers

PMID28337251
PMCPMC5350298
OpenAlexW2593821039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.