Evidence map›Paper›PMID 28336974›Full record

ReviewScientific reports2017

PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology.

M Sollini, L Cozzi, L Antunovic, A Chiti, M Kirienko

3 registry-linked trialsAbstract readReview
In one paragraph

Review in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 98 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03648151 completednot on this map

Influence of PET/CT Radiomic Features on the Outcome of Lung Cancer Patients

TypeobservationalSponsorThe First Affiliated Hospital of Shanxi Medical UniversityRan2010 to 2019Enrolled1,000ConditionsLung Cancer, Image, Body
NCT04276025 completednot on this map

Relationship Between Histopathological Features, Mutation Status, 18F-FDG PET/CT Radiomic Imaging Parameters as Well as Clinical Outcome in Patients With Treatment-naïve Non-small Cell Lung Cancer

TypeobservationalSponsorKlinikum Bayreuth GmbHRan2016 to 2020Enrolled2,000ConditionsNSCLCArmsClinical routine F18-FDG-PET/CT, molecular pathology and clinical outcome
NCT06779734 completednot on this mapstarted 2020, after this paper: background citation

Radiomic Features of Tumor and of Liver-Tumor Interface in Patients With Colorectal Liver Metastases. Identification of New Prognostic Biomarkers.

TypeobservationalSponsorIstituto Clinico HumanitasRan2020 to 2024Enrolled400ConditionsLiver Metastases From Colorectal Cancer (mCRC)
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Repeatability and Reproducibility of Radiomic Features: A Systematic Review.International journal of radiation oncology, biology, physics · 2018
    Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Long-axial field-of-view PET/CT improves radiomics feature reliability.European journal of nuclear medicine and molecular imaging · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Impact of respiratory motion onJournal of applied clinical medical physics · 2023
    Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M SolliniDepartment of Biomedical Sciences, Humanitas University, via Manzoni, 113-20089, Rozzano, (Milan), Italy. martina.sollini@cancercenter.humanitas.it.
L CozziDepartment of Biomedical Sciences, Humanitas University, via Manzoni, 113-20089, Rozzano, (Milan), Italy.
L AntunovicNuclear Medicine Unit, Humanitas Clinical and Research Center, via Manzoni, 56-20089, Rozzano, (Milan), Italy.
A ChitiDepartment of Biomedical Sciences, Humanitas University, via Manzoni, 113-20089, Rozzano, (Milan), Italy.ORCID 0000-0002-5806-1856
M KirienkoDepartment of Biomedical Sciences, Humanitas University, via Manzoni, 113-20089, Rozzano, (Milan), Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging with positron emission tomography (PET)/computed tomography (CT) is crucial in the management of cancer because of its value in tumor staging, response assessment, restaging, prognosis and treatment responsiveness prediction. In the last years, interest has grown in texture analysis which provides an "in-vivo" lesion characterization, and predictive information in several malignances including NSCLC; however several drawbacks and limitations affect these studies, especially because of lack of standardization in features calculation, definitions and methodology reporting. The present paper provides a comprehensive review of literature describing the state-of-the-art of FDG-PET/CT texture analysis in NSCLC, suggesting a proposal for harmonization of methodology.

Indexed as

Carcinoma, Non-Small-Cell LungHumansImage Interpretation, Computer-AssistedLung NeoplasmsPositron Emission Tomography Computed TomographySensitivity and Specificity

Identifiers

PMID28336974
PMCPMC5428425

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.