ArticleScientific reports2017
Altered spontaneous brain activity in chronic smokers revealed by fractional ramplitude of low-frequency fluctuation analysis: a preliminary study.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- The structural and functional brain alternations in tobacco use disorder: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Pooled it
- The resting-state brain activity signatures for addictive disorders.Med (New York, N.Y.) · 2024Pooled it
- Microstructural brain changes in Buerger's disease and smokers: a case-control study using diffusion tensor imaging.BMC medical imaging · 2026Article
- Self-supervised multimodal learning for group inferences from MRI data: Discovering disorder-relevant brain regions and multimodal links.NeuroImage · 2024Article
- Increased spontaneous activity of the superior frontal gyrus with reduced functional connectivity to visual attention areas and cerebellum in male smokers.Frontiers in human neuroscience · 2023Article
- Reciprocal modulation between cigarette smoking and internet gaming disorder on participation coefficient within functional brain networks.Brain imaging and behavior · 2022Article
- RP-Rs-fMRIomics as a Novel Imaging Analysis Strategy to Empower Diagnosis of Brain Gliomas.Cancers · 2022Article
- Increased amplitude of hippocampal low frequency fluctuations in early psychosis: A two-year follow-up study.Schizophrenia research · 2022Article
- Cognition, Aryl Hydrocarbon Receptor Repressor Methylation, and Abstinence Duration-Associated Multimodal Brain Networks in Smoking and Long-Term Smoking Cessation.Frontiers in neuroscience · 2022Article
- Regional Homogeneity Abnormalities and Its Correlation With Impulsivity in Male Abstinent Methamphetamine Dependent Individuals.Frontiers in molecular neuroscience · 2021Article
- Dynamic Neuroimaging Biomarkers of Smoking in Young Smokers.Frontiers in psychiatry · 2020Article
- Interaction Between Smoking and Internet Gaming Disorder on Spontaneous Brain Activity.Frontiers in psychiatry · 2020Article
- Increased thalamic volume and decreased thalamo-precuneus functional connectivity are associated with smoking relapse.NeuroImage. Clinical · 2020Article
- Temporal dynamics of spontaneous default-mode network activity mediate the association between reappraisal and depression.Social cognitive and affective neuroscience · 2018Article
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although a substantial body of previous functional magnetic resonance imaging (fMRI) studies have revealed different brain responses to external stimuli in chronic cigarette smokers compared with nonsmokers, only a few studies assessed brain spontaneous activity in the resting state in chronic smokers. The aim of this study was to investigate alterations of brain activity during the resting state in chronic smokers using fractional amplitude of low-frequency fluctuation (fALFF). In the present study, 55 smokers and 49 healthy nonsmokers were included. All the subjects underwent resting-state fMRI scans and the data were analyzed by the fALFF approach. The smokers showed significantly decreased fALFF in the left precuneus, right inferior temporal and occipital gyrus(ITG/IOG), while significantly increased fALFF in the right caudate. Subsequent correlation analysis revealed that the fALFF values of the left precuneus and right ITG/IOG were positively correlated with years of smoking across the smokers. This resting-state fMRI study suggests that the changed spontaneous neuronal activity, as reflected by the fALFF, in these regions may be implicated in the underlying the pathophysiology of smoking.
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