Evidence map›Paper›PMID 28336873›Full record

ArticleNanomaterials (Basel, Switzerland)2017

Synthesis, Characterization, and Biological Evaluation of Nanostructured Hydroxyapatite with Different Dimensions.

Zhen Geng, Qin Yuan, Xianglong Zhuo, Zhaoyang Li, Zhenduo Cui, Shengli Zhu, Yanqin Liang, Yunde Liu, Huijing Bao, Xue Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Research Progress of Bone Grafting: A Comprehensive Review.International journal of nanomedicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Zhen GengTianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. nanboshan1987@163.com.
Qin YuanSchool of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. m13752208393@163.com.
Xianglong ZhuoDepartment of Spinal Surgery, Liuzhou Worker's Hospital, Liuzhou 545001, China. doctorzhuo@139.com.
Zhaoyang LiTianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. zyli@tju.edu.cn.
Zhenduo CuiTianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. zdcui@tju.edu.cn.
Shengli ZhuTianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. slzhu@tju.edu.cn.
Yanqin LiangTianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. yqliang@tju.edu.cn.
Yunde LiuSchool of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. yundeliu@126.com.
Huijing BaoSchool of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. kris_10713@126.com.
Xue LiSchool of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. nicolelea@163.com.
Qianyu HuoSchool of Laboratory Medicine, Tianjin Medical University, Tianjin 300072, China. huo.qianyu@163.com.
Xianjin YangTianjin Key Laboratory of Composite and Functional Materials, School of Materials Science and Engineering, Tianjin University, Tianjin 300072, China. xjyang@tju.edu.cn.
Tianjin University · CNTianjin Medical University · CNLiuzhou General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanosized hydroxyapatite (HA) is a promising candidate for a substitute for apatite in bone in biomedical applications. Furthermore, due to its excellent bone bioactivity, nanosized strontium-substituted HA (SrHA) has aroused intensive interest. However, the size effects of these nanoparticles on cellular bioactivity should be considered. In this study, nanosized HA and SrHA with different dimensions and crystallization were synthesized by hydrothermal methods. The phase, crystallization and chemical composition were analyzed by X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR), respectively. The morphology was observed under field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM). The degradation behaviors of the samples were monitored by determining the ions release profile with inductively coupled plasma mass spectrometry (ICP-MS). The releasing behavior of Ca

Indexed as

absorbable implantsbiocompatible materialscrystallizationnanostructured materialssurface properties

Identifiers

PMID28336873
PMCPMC5333023
OpenAlexW2587784406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.