Evidence map›Paper›PMID 28336821›Full record

ArticlePhysiological reports2017

Hyperbaric oxygen therapy reduces renal lactate production.

Thomas S Nørlinger, Per Mose Nielsen, Haiyun Qi, Emmeli Mikkelsen, Kasper Hansen, Nikolaj H Schmidt, Michael Pedersen, Peter Agger, Fredrik Palm, Christoffer Laustsen

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. EngineeredACS synthetic biology · 2025
    Article
  2. EngineeredbioRxiv : the preprint server for biology · 2024
    Article
  3. Review
  4. Hyperpolarized Carbon (Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  5. Article
  6. HyperpolarisedMagma (New York, N.Y.) · 2020
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Thomas S NørlingerDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark.
Per Mose NielsenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark.
Haiyun QiDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark.
Emmeli MikkelsenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark.
Kasper HansenDepartment of Clinical Medicine, Comparative Medicine Lab, Aarhus University, Aarhus, Denmark.
Nikolaj H SchmidtDepartment of Clinical Medicine, Comparative Medicine Lab, Aarhus University, Aarhus, Denmark.
Michael PedersenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark.
Peter AggerDepartment of Pediatrics, Aarhus University Hospital, Aarhus, Denmark.
Fredrik PalmDepartment of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Christoffer LaustsenDepartment of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark cl@clin.au.dk.
Aarhus University Hospital · DKAarhus University · DKUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrarenal hypoxia is an acknowledged factor contributing to the development of diabetic nephropathy. Hyperbaric oxygen (HBO) therapy is a well-known adjuvant treatment for several medical conditions, such as decompression sickness, infections, and wound healing. The underlying metabolic response of HBO is largely unknown. In this study, we investigated the effect of HBO on the intrarenal metabolic alteration in diabetes. Hyperpolarized [1-

Indexed as

Hyperbaric OxygenationAnimalsDiabetes Mellitus, ExperimentalDiabetic NephropathiesFemaleKidneyLactic AcidRatsRats, WistarLactic AcidHyperpolarizationkidneykidney metabolismMRItype 1 diabetes

Identifiers

PMID28336821
PMCPMC5371573
OpenAlexW2601764999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.