Evidence map›Paper›PMID 28336747›Full record

Trial reportBMJ open2017

Cross-sectional associations between dietary intake and carotid intima media thickness in type 2 diabetes: baseline data from a randomised trial.

Laura Chiavaroli, Arash Mirrahimi, Christopher Ireland, Sandra Mitchell, Sandhya Sahye-Pudaruth, Judy Coveney, Omodele Olowoyeye, Darshna Patel, Russell J de Souza, Livia S A Augustin and 11 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01063374 (Low Glycemic Index Diets to Improve Glycemic Control and Cardiovascular Disease in Type 2 Diabetics), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01063374 phase2completednot on this map

Low Glycemic Index Diets to Improve Glycemic Control and Cardiovascular Disease in Type 2 Diabetics

TypeinterventionalSponsorUniversity of TorontoRan2010 to 2016Enrolled169ConditionsType 2 DiabetesArmslow glycemic diet instruction, high cereal fibre diet instruction
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 2 countries.

Laura ChiavaroliDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Arash MirrahimiClinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, Ontario, Canada.
Christopher IrelandDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Sandra MitchellDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Sandhya Sahye-PudaruthDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Judy CoveneyClinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, Ontario, Canada.
Omodele OlowoyeyeDepartment of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Darshna PatelDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Russell J de SouzaClinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, Ontario, Canada.
Livia S A AugustinClinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, Ontario, Canada.
Balachandran BashyamDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Sathish Chandra PichikaClinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, Ontario, Canada.
Sonia Blanco MejiaDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Stephanie K NishiDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Lawrence A LeiterDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Robert G JosseDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Gail E McKeown-EyssenDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Alan R MoodyDepartment of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Cyril W C KendallDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
John L SievenpiperDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
David J A JenkinsDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
St. Michael's Hospital · CAUniversity of Toronto · CAImpact · CAQueen's University · CASunnybrook Health Science Centre · CA

Funding

CIHR
6 · The paper itself

Abstract

objectiveTo assess associations between dietary intake and carotid intima media thickness (CIMT) by carotid ultrasound (CUS), a surrogate marker of cardiovascular disease (CVD) risk, in those with type 2 diabetes.

designCross-sectional analysis of baseline data from 325 participants from three randomised controlled trials collected in the same way.

settingRisk Factor Modification Centre, St. Michael's Hospital, Toronto, Canada.

participants325 participants with type 2 diabetes, taking oral antidiabetic agents, with an HbA1c between 6.5% and 8.0% at screening, without a recent cardiovascular event.

main outcome measuresCIMT by CUS and associations with dietary intake from 7-day food records, as well as anthropometric measures and fasting serum samples.

resultsCIMT was significantly inversely associated with dietary pulse intake (β=-0.019, p=0.009), available carbohydrate (β=-0.004, p=0.008), glycaemic load (β=-0.001, p=0.007) and starch (β=-0.126, p=0.010), and directly associated with total (β=0.004, p=0.028) and saturated (β=0.012, p=0.006) fat intake in multivariate regression models adjusted for age, smoking, previous CVD event, blood pressure medication, antidiabetic medication and ultrasonographer.

conclusionsLower CIMT was significantly associated with greater consumption of dietary pulses and carbohydrates and lower total and saturated fat intake, suggesting a potential role for diet in CVD risk management in type 2 diabetes. Randomised controlled trials are anticipated to explore these associations further. TRIAL REGISTRATION NUMBER: NCT01063374.

Indexed as

CanadaCardiovascular DiseasesCarotid Intima-Media ThicknessCross-Sectional StudiesDiabetes Mellitus, Type 2DietFemaleHumansMaleMiddle AgedRisk FactorsDIABETES & ENDOCRINOLOGYNUTRITION & DIETETICS

Identifiers

PMID28336747
PMCPMC5372138
OpenAlexW2604091766

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.