Evidence map›Paper›PMID 28336721›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis.

Dong Zhou, Haiyan Fu, Lu Zhang, Ke Zhang, Yali Min, Liangxiang Xiao, Lin Lin, Sheldon I Bastacky, Youhua Liu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 124 citations in OpenAlex.

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  16. Cell-cell communication in kidney fibrosis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Review
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Dong ZhouDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Haiyan FuState Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China; and.
Lu ZhangDivision of Nephrology, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Ke ZhangDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Yali MinDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Liangxiang XiaoState Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China; and.
Lin LinDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Sheldon I BastackyDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Youhua LiuDepartment of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; liuy@upmc.edu.
University of Pittsburgh · USSouthern Medical University · CNNanfang Hospital · CNNanjing University of Chinese Medicine · CN

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
Tenancin-C as a major component of the fibrogenic nicheR01DK064005 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAN, RODERICK JASON · 2003 to 2021
$5.1M
Central role of fibroblasts in kidney repair and disease after AKIR01DK106049 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LIU, YOUHUA · 2015 to 2018
$1.4M
Beta-catenin Signaling and Podocyte DysfunctionR01DK091239 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LIU, YOUHUA · 2012 to 2015
$895k
NIDDK NIH HHS P30 DK079307NIDDK NIH HHS R01 DK064005NIDDK NIH HHS R01 DK091239NIDDK NIH HHS R01 DK106049
6 · The paper itself

Abstract

Cell-cell communication

Indexed as

AnimalsCell CommunicationCell ProliferationCells, CulturedFibroblastsFibrosisHumansKidneyKidney TubulesMiceMice, KnockoutRatsWnt ProteinsWnt Signaling PathwayWnt Proteinschronic kidney diseasefibroblastrenal fibrosisWntlessWnt signaling

Identifiers

PMID28336721
PMCPMC5533232
OpenAlexW2603641223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.