ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2017
High-resolution anatomic correlation of cyclic motor patterns in the human colon: Evidence of a rectosigmoid brake.
Article in American journal of physiology. Gastrointestinal and liver physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Clinical Relevance of the Rectosigmoid Brake in Surgical Disorders and Therapies: A Systematic Review of Colonic Manometry Studies.Neurogastroenterology and motility · 2026Pooled it
- Post-operative colonic manometry in children with anorectal malformations: A systematic review.Neurogastroenterology and motility · 2022Pooled it
- Safety and efficacy of laxatives after major abdominal surgery: systematic review and meta-analysis.BJS open · 2020Pooled it
- A Biophysical Model of Human Colonic Motor Pattern Generation in Health and Disease.bioRxiv : the preprint server for biology · 2026Article
- Right extended hemicolectomy with ileo-descending anastomosis is associated with prolonged postoperative ileus and longer hospital stay compared to right or left hemicolectomy.International journal of colorectal disease · 2025Article
- Automated digital analysis of propagated contractions recorded during fasting using high resolution small intestinal manometry in healthy participants.Npj gut and liver · 2025Article
- The Functional Implications of Transanal Irrigation: Insights from Pathophysiology and Clinical Studies of Neurogenic Bowel Dysfunction.Journal of clinical medicine · 2024Review
- Validation of body surface colonic mapping (BSCM) against high resolution colonic manometry for evaluation of colonic motility.Scientific reports · 2024Article
- To explore the pathogenesis of anterior resection syndrome by magnetic resonance imaging rectal defecography.World journal of gastrointestinal surgery · 2024Article
- Imaging analytical technique to assess gastrointestinal motility in vivo using zebrafish larvae with diabetes mellitus-like traits.PloS one · 2024Article
- Article
- Evidence that RXFP4 is located in enterochromaffin cells and can regulate production and release of serotonin.Bioscience reports · 2023Article
- Post-Operative Anorectal Manometry in Children following Anorectal Malformation Repair: A Systematic Review.Journal of clinical medicine · 2023Review
- Regional Differences in Intestinal Contractile Responses to Radial Stretch in the Human Lower Gastrointestinal Tract.Journal of neurogastroenterology and motility · 2023Article
- Management of Low Anterior Resection Syndrome (LARS) Following Resection for Rectal Cancer.Cancers · 2023Review
- Long-term functional outcome after tubular laparoscopic sigmoid resection for diverticular disease.International journal of colorectal disease · 2023Article
- Circadian rhythms in colonic function.Frontiers in physiology · 2023Review
- Faecal incontinence is associated with an impaired rectosigmoid brake and improved by sacral neuromodulation.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Article
- Faecal incontinence in adults.Nature reviews. Disease primers · 2022Review
- Comparison of prolonged postoperative ileus between laparoscopic right and left colectomy under enhanced recovery after surgery: a propensity score matching analysis.World journal of surgical oncology · 2022Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Colonic cyclic motor patterns (CMPs) have been hypothesized to act as a brake to limit rectal filling. However, the spatiotemporal profile of CMPs, including anatomic origins and distributions, remains unclear. This study characterized colonic CMPs using high-resolution (HR) manometry (72 sensors, 1-cm resolution) and their relationship with proximal antegrade propagating events. Nine healthy volunteers were recruited. Recordings were performed over 4 h, with a 700-kcal meal given after 2 h. Propagating events were visually identified and analyzed by pattern, origin, amplitude, extent of propagation, velocity, and duration. Manometric data were normalized using anatomic landmarks identified on abdominal radiographs. These were mapped over a three-dimensional anatomic model. CMPs comprised a majority of detected propagating events. Most occurred postprandially and were retrograde propagating events (84.9 ± 26.0 retrograde vs. 14.3 ± 11.8 antegrade events/2 h,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.